Evidence map›Paper›PMID 29988883›Full record

ArticleChronic diseases and translational medicine2018

Air pollutants and early origins of respiratory diseases.

Dasom Kim, Zi Chen, Lin-Fu Zhou, Shou-Xiong Huang

Open access · goldAbstract read
In one paragraph

Article in Chronic diseases and translational medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed, 5 pooled it
15.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

90 citing papers in PubMed, 5 syntheses or guidelines pooled it, 294 citations in OpenAlex.

  1. Micro and Nanoplastics and Obstetric Outcomes in Humans and Animals: A Systematic Review.International journal of environmental research and public health · 2026
    Pooled it
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  6. Review
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  12. Measuring historical pollution: Natural history collections as tools for public health and environmental justice research.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  13. Air Pollution and Effects of Tropospheric Ozone (OInternational journal of environmental research and public health · 2025
    Review
  14. The association between PMAIMS public health · 2025
    Article
  15. Article
  16. Article
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30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Dasom KimDepartment of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, OH 45249, USA.
Zi ChenDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China.
Lin-Fu ZhouDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China.
Shou-Xiong HuangDepartment of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, OH 45249, USA.
University of Cincinnati Medical Center · USJiangsu Province Hospital · CNNanjing Medical University · CN

Funding

REPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGY RESEARCHP30ES006096 · NIEHS · UNIVERSITY OF CINCINNATI · PI PINNEY, SUSAN MENGEL · 1992 to 2022
$35.4M
Antigen metabolomics for mucosal-associated invariant T cells in tuberculosisR21AI115358 · NIAID · UNIVERSITY OF CINCINNATI · PI HUANG, SHOUXIONG · 2015 to 2016
$435k
NIAID NIH HHS R21 AI115358NIEHS NIH HHS P30 ES006096
6 · The paper itself

Abstract

Air pollution is a global health threat and causes millions of human deaths annually. The late onset of respiratory diseases in children and adults due to prenatal or perinatal exposure to air pollutants is emerging as a critical concern in human health. Pregnancy and fetal development stages are highly susceptible to environmental exposure and tend to develop a long-term impact in later life. In this review, we briefly glance at the direct impact of outdoor and indoor air pollutants on lung diseases and pregnancy disorders. We further focus on lung complications in later life with early exposure to air pollutants. Epidemiological evidence is provided to show the association of prenatal or perinatal exposure to air pollutants with various adverse birth outcomes, such as preterm birth, lower birth weight, and lung developmental defects, which further associate with respiratory diseases and reduced lung function in children and adults. Mechanistic evidence is also discussed to support that air pollutants impact various cellular and molecular targets at early life, which link to the pathogenesis and altered immune responses related to abnormal respiratory functions and lung diseases in later life.

Indexed as

Air pollutantsEarly disease originParticulate matterPolycyclic aromatic hydrocarbonRespiratory diseases

Identifiers

PMID29988883
PMCPMC6033955
OpenAlexW2807476580

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.