Evidence map›Paper›PMID 29988876›Full record

ReviewAsian journal of urology2018

The aging bladder insights from animal models.

Lori A Birder, Aura F Kullmann, Christopher R Chapple

Open access · diamondAbstract readReview
In one paragraph

Review in Asian journal of urology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 27 citations in OpenAlex.

  1. PIEZO1-mediated mechanosensation links aging to bladder dysfunction.bioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Association of detrusor underactivity with aging and metabolic syndrome: suggestions from animal models.Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Study of Longitudinal Aging in Mice: Presentation of Experimental Techniques.The journals of gerontology. Series A, Biological sciences and medical sciences · 2021
    Article
  14. Review
  15. Article
  16. Article
  17. Micturition defects and altered bladder function in theAmerican journal of clinical and experimental urology · 2020
    Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Lori A BirderUniversity of Pittsburgh School of Medicine, Department of Pharmacology, Pittsburgh, PA, USA.
Aura F KullmannUniversity of Pittsburgh School of Medicine, Department of Medicine, Pittsburgh, PA, USA.
Christopher R ChappleDepartment of Urology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
University of Pittsburgh · USSheffield Teaching Hospitals NHS Foundation Trust · GB

Funding

Bladder Mucosal Dysfunction During AgingR01AG056944 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI APODACA, GERARD L, BIRDER, LORI A · 2018 to 2022
$3.2M
NIA NIH HHS R01 AG056944
6 · The paper itself

Abstract

Alterations in bladder function with aging are very common and are very likely to represent an increasing healthcare problem in the years to come with the general aging of the population. In this review the authors describe the prevalence of lower urinary tract symptoms (LUTS) and comment upon potential mechanisms which may be responsible for the increasing prevalence of lower LUTS with increasing age, based on laboratory studies. It is clear that there is a complex interplay between the various components of the neural innervation structure of the bladder in leading to changes with age, which are likely to underpin the LUTS which are seen in the aging bladder.

Indexed as

AgingBladder functionEtiology of lower urinary tract symptomsLower urinary tract symptoms

Identifiers

PMID29988876
PMCPMC6033201
OpenAlexW2617823621

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.