Evidence map›Paper›PMID 29988841›Full record

ReviewJournal of advanced research2018

A review on pregnancy complicated by ovarian epithelial and non-epithelial malignant tumors: Diagnostic and therapeutic perspectives.

Stergios Boussios, Michele Moschetta, Konstantina Tatsi, Alexandros K Tsiouris, Nicholas Pavlidis

Open access · goldAbstract readReview
In one paragraph

Review in Journal of advanced research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
1.9field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 67 citations in OpenAlex.

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  12. Identification ofInternational journal of general medicine · 2024
    Article
  13. Article
  14. Article
  15. Tumor Markers in Differential Diagnosis of Benign Ovarian Masses.International journal of women's health · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Yolk Sac Tumor of the Ovary in Mosaic 46XX Turner Syndrome.International journal of women's health · 2024
    Article
  20. Clinical Challenges in the Management of Malignant Ovarian Germ Cell Tumours.International journal of environmental research and public health · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Stergios BoussiosMedical School, University of Ioannina, Stavros Niarchou Avenue, 45110 Ioannina, Greece.
Michele MoschettaDrug Development Unit, Sarah Cannon Research Institute, 93 Harley Street, London W1G 6AD, UK.
Konstantina TatsiGynaecology Unit, General Hospital "G. Hatzikosta", Makrigianni Avenue, 45001 Ioannina, Greece.
Alexandros K TsiourisDepartment of Biological Applications & Technology, University of Ioannina, Stavros Niarchou Avenue, 45110 Ioannina, Greece.
Nicholas PavlidisMedical School, University of Cyprus, Old road Lefkosias Lemesou, No. 215/6, 2029 Aglantzia, Nicosia, Cyprus.
University of Ioannina · GRGeneral Hospital of Ioannina G. Hatzikosta · GRSarah Cannon Research Institute · GBUniversity of Cyprus · CY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The management of gestational ovarian cancer can be challenging because of the risk of fetal wastage, and the possibility of treatment-related complications to the fetus; it is based on insufficient data from retrospective studies and case series. Here, a literature review of the diagnostic and surgical approaches to the gestational ovarian cancer has been performed; moreover, data on safety of chemotherapeutic treatments in pregnancy, including both oncologic and fetal outcomes, have also been reviewed. Up to now, 193 cases of ovarian cancers during pregnancy have been reported in the English literature. Treatment of ovarian malignancies during pregnancy depends on histology, stage, and gestational weeks. When possible, surgical excision is indicated, and fertility-sparing surgery can be offered to stage I epithelial ovarian tumours (EOC), germ cell ovarian, or sex-cord stromal ovarian tumours. Neoadjuvant and/or adjuvant chemotherapy for advanced ovarian tumours is indicated as in non-pregnant women. Administration of chemotherapy after the first trimester, can cause fetal growth restriction, while being seemingly safe. The therapeutic approach of ovarian cancer in pregnancy should be individualized and intended in specialized centers.

Indexed as

ChemotherapyKrukenbergOvarian tumoursPregnancySurgery

Identifiers

PMID29988841
PMCPMC6032492
OpenAlexW2791742117

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.