Evidence map›Paper›PMID 29988758›Full record

ArticleThe World Allergy Organization journal2018

Management of chronic spontaneous urticaria: a worldwide perspective.

Pavel Kolkhir, Dmitry Pogorelov, Razvigor Darlenski, Marco Caminati, Luciana Kase Tanno, Duy Le Pham, Alexei Gonzalez-Estrada, Darío Antolín-Amérigo, Ves Dimov, Karsten Weller and 4 more

Open access · goldAbstract read
In one paragraph

Article in The World Allergy Organization journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Systemic Treatments for Chronic Spontaneous Urticaria: Anti-IgE and Beyond.The journal of allergy and clinical immunology. In practice · 2026
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. A Patient Charter for Chronic Urticaria.Advances in therapy · 2024
    Article
  12. Review
  13. Review
  14. Urticaria.Nature reviews. Disease primers · 2022
    Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 12 institutions in 11 countries.

Pavel Kolkhir1Division of Immune-mediated skin diseases, I.M. Sechenov First Moscow State Medical University, 119991, Trubeckaya str., 8/2, Moscow, Russian Federation.ORCID 0000-0001-5380-8132
Dmitry Pogorelov2Department of Infection and Immunity, Luxembourg Institute of Health, Esch-sur-Alzette, Luxembourg.
Razvigor Darlenski3Department of Dermatology and Venereology, Trakia University, Stara Zagora, Bulgaria.
Marco Caminati4Asthma Center and Allergy Unit, Verona University Hospital, Verona, Italy.
Luciana Kase Tanno5Hospital Sírio Libanês and Post-graduation Program in Health Sciences of IAMSPE São Paulo, São Paulo, Brazil.
Duy Le Pham7Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Viet Nam.
Alexei Gonzalez-Estrada8Division of Allergy, Pulmonary and Sleep Medicine, Department of Medicine, Mayo Clinic, Jacksonville, Florida, USA.
Darío Antolín-Amérigo9Servicio de Enfermedades del Sistema Inmune-Alergia, Hospital Universitario Príncipe de Asturias, Madrid, Spain.
Ves Dimov11Department of Allergy and Immunology, Cleveland Clinic Florida, Weston, Florida, USA.
Karsten Weller12Department of Dermatology and Allergy, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Mario Sánchez-Borges13Allergy and Clinical Immunology Department, Centro Medico Docente La Trinidad, Caracas, Venezuela.
Ignacio AnsoteguiDepartment of Allergy and Immunology, Hospital Quirónsalud Bizkaia, Bilbao, Spain.
Marcus Maurer12Department of Dermatology and Allergy, Charité - Universitätsmedizin Berlin, Berlin, Germany.
WAO Junior Members Group
Charité - Universitätsmedizin Berlin · DECentro Médico Docente La Trinidad · VECleveland Clinic Florida · USHo Chi Minh City University of Science · VNHospital Quirónsalud Barcelona · ESJacksonville College · USLuxembourg Institute of Health · LUSechenov University · RUSorbonne Université · FRTrakia University · BGUniversidad de Alcalá · ESUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe approaches to the diagnosis and treatment of chronic spontaneous urticaria (CSU) differ in various parts of the world. We sought to determine the adherence to international and national urticaria guidelines as well as the motives to deviate from the guidelines among physicians worldwide.

methodsA web-based questionnaire was created and launched via e-mail by the World Allergy Organization (WAO) to representatives of all WAO Member Societies, the members of the American Academy of Allergy, Asthma & Immunology (AAAAI) and the members of the WAO Junior Members Group (JMG), regardless of the specialty, affiliation, or nationality in March 2017.

resultsWe received 1140 completed surveys from participating physicians from 99 countries. Virtually all participants (96%) were aware of at least one urticaria guideline and reported that they follow a guideline. However, one in five physicians who follow a guideline (22%) reported to deviate from it. Reliance on own clinical experience is the most frequent reason for deviation from guidelines or not following them (44%). Young (< 40 years) and less experienced physicians more often follow a guideline and less often deviate than older and experienced ones. Physicians who follow a urticaria guideline showed higher rates of routinely ordering a complete blood count, the erythrocyte sedimentation rate, C-reactive protein, anti-thyroid antibodies, and thyroid-stimulating hormone and of performing the autologous serum skin test as compared to those who do not. Physicians who follow a urticaria guideline showed higher rates of using second generation antihistamines as their first-line treatment of CSU (

conclusionsPhysicians' characteristics (e.g. age, clinical experience, and specialty) and country specifics and regional features (e.g. availability of drugs for CSU treatment) importantly influence adherence to urticaria guidelines and CSU patient care and should be addressed in more detail in future research.

Indexed as

Chronic spontaneous urticariaGlobal surveyGuideline adherenceGuidelinesUrticaria managementUrticaria treatmentWorldwide

Identifiers

PMID29988758
PMCPMC6030778
OpenAlexW2809814513

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.