Evidence map›Paper›PMID 29988757›Full record

ArticleInternational journal of chronic obstructive pulmonary disease2018

The Efficiency Index (EFFi), based on volumetric capnography, may allow for simple diagnosis and grading of COPD.

Linnea Jarenbäck, Ellen Tufvesson, Jaro Ankerst, Leif Bjermer, Björn Jonson

Registry-linked trialAbstract read
In one paragraph

Article in International journal of chronic obstructive pulmonary disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04814797 (The Study of Capnography for the Follow-up of Cystic Fibrosis Children With or Without Gas Trapping), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04814797 unknown statusnot on this mapstarted 2021, after this paper: background citation

The Study of Capnography for the Follow-up of Cystic Fibrosis Children With or Without Gas Trapping

TypeobservationalSponsorCentral Hospital, Nancy, FranceRan2021 to 2021Enrolled76ConditionsCystic FibrosisArmsCapnography data included in Lung Clearance Index measurement
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Development and preliminary tests of a portable volumetric capnograph for outpatient use.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2025
    Article
  2. Article
  3. Observational
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Linnea JarenbäckRespiratory Medicine and Allergology, Department of Clinical Sciences, Skåne University Hospital, Lund University, Lund, Sweden, linnea.jarenback@med.lu.se.
Ellen TufvessonRespiratory Medicine and Allergology, Department of Clinical Sciences, Skåne University Hospital, Lund University, Lund, Sweden, linnea.jarenback@med.lu.se.
Jaro AnkerstRespiratory Medicine and Allergology, Department of Clinical Sciences, Skåne University Hospital, Lund University, Lund, Sweden, linnea.jarenback@med.lu.se.
Leif BjermerRespiratory Medicine and Allergology, Department of Clinical Sciences, Skåne University Hospital, Lund University, Lund, Sweden, linnea.jarenback@med.lu.se.
Björn JonsonClinical Physiology, Department of Clinical Sciences, Skåne University Hospital, Lund University, Lund, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Spirometry, the main tool for diagnosis and follow-up of COPD, incompletely describes the disease. Based on volumetric capnography (VCap), an index was developed for the diagnosis and grading of COPD, aimed as a complement or alternative to spirometry. Methods: Nine non-smokers, 10 smokers/former smokers without COPD and 54 smokers/former smokers with COPD were included in the study. Multiple breath washout of N Results: EFFi increased with increased Global initiative for chronic Obstructive Lung Disease (GOLD) stage and the majority of subjects in GOLD 2 and all subjects in GOLD 3 and 4 could be diagnosed as having COPD using the lower 95% confidence interval of the healthy group. EFFi also correlated with N Conclusion: EFFi measures efficiency of tidal CO

Indexed as

AgedBreath TestsCapnographyCarbon DioxideFemaleForced Expiratory VolumeHumansMaleMiddle AgedPulmonary Disease, Chronic ObstructiveSpirometryVital CapacityCarbon Dioxidecarbon dioxidechronic obstructive pulmonary diseasesingle breathvolumetric capnography

Identifiers

PMID29988757
PMCPMC6029593

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.