Evidence map›Paper›PMID 29988661›Full record

ArticleClinical case reports2018

Cyclic thrombocytopenia with statistically significant neutrophil oscillations.

Gabriel P Langlois, Donald M Arnold, Jayson Potts, Brian Leber, David C Dale, Michael C Mackey

Open access · goldAbstract readCase Reports
In one paragraph

Article in Clinical case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. The highs and lows of cyclic thrombocytopenia.British journal of haematology · 2024
    Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Gabriel P LangloisDivision of Applied Mathematics Brown University Providence RI USA.ORCID 0000-0002-1845-9536
Donald M ArnoldDivision of Hematology and Thromboembolism Department of Medicine McMaster University Hamilton ON Canada.
Jayson PottsDepartment of Medicine General Internal Medicine University of British Columbia Vancouver BC Canada.
Brian LeberDivision of Hematology and Thromboembolism Department of Medicine McMaster University Hamilton ON Canada.
David C DaleDepartment of Medicine University of Washington Seattle WA USA.
Michael C MackeyDepartments of Physiology, Physics, and Mathematics McGill University Montreal QC Canada.
Thrombosis and Atherosclerosis Research Institute · CABrown University · USMcGill University · CAUniversity of British Columbia · CAUniversity of Washington · US

Funding

Severe Chronic Neutropenia International RegistryR24AI049393 · NIAID · UNIVERSITY OF WASHINGTON · PI DALE, DAVID CHANDLER · 2004 to 2019
$10.6M
NIAID NIH HHS R24 AI049393
6 · The paper itself

Abstract

Cyclic thrombocytopenia is often misdiagnosed as immune thrombocytopenia due to similar clinical features, a fact of significance because cyclic thrombocytopenia generally responds poorly to treatments used successfully in immune thrombocytopenia. A precise diagnosis must establish the statistical significance of periodicity of the platelet counts using statistical methods (eg, Lomb-Scargle periodogram).

Indexed as

bleedingcyclic neutropeniacyclic thrombocytopeniaimmune thrombocytopeniathrombopoietin

Identifiers

PMID29988661
PMCPMC6028424
OpenAlexW2807575667

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.