Evidence map›Paper›PMID 29988555›Full record

ArticleFrontiers in molecular neuroscience2018

Somatic Accumulation of GluA1-AMPA Receptors Leads to Selective Cognitive Impairments in Mice.

David M Bannerman, Thilo Borchardt, Vidar Jensen, Andrey Rozov, Nadia N Haj-Yasein, Nail Burnashev, Daniel Zamanillo, Thorsten Bus, Isabel Grube, Giselind Adelmann and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 6 countries.

David M BannermanDepartment of Experimental Psychology, University of Oxford, Oxford, United Kingdom.
Thilo BorchardtDepartments of Molecular Neurobiology and Cell Physiology, Max Planck Institute for Medical Research, Heidelberg, Germany.
Vidar JensenDepartment of Physiology, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Andrey RozovDepartments of Molecular Neurobiology and Cell Physiology, Max Planck Institute for Medical Research, Heidelberg, Germany.
Nadia N Haj-YaseinDepartment of Physiology, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Nail BurnashevDepartments of Molecular Neurobiology and Cell Physiology, Max Planck Institute for Medical Research, Heidelberg, Germany.
Daniel ZamanilloDepartments of Molecular Neurobiology and Cell Physiology, Max Planck Institute for Medical Research, Heidelberg, Germany.
Thorsten BusDepartments of Molecular Neurobiology and Cell Physiology, Max Planck Institute for Medical Research, Heidelberg, Germany.
Isabel GrubeInstitute of Anatomy and Cell Biology, University of Freiburg, Freiburg, Germany.
Giselind AdelmannInstitute of Anatomy and Cell Biology, University of Freiburg, Freiburg, Germany.
J Nicholas P RawlinsDepartment of Experimental Psychology, University of Oxford, Oxford, United Kingdom.
Rolf SprengelDepartments of Molecular Neurobiology and Cell Physiology, Max Planck Institute for Medical Research, Heidelberg, Germany.
Max Planck Institute for Medical Research · DEUniversity of Freiburg · DEUniversity of Oslo · NOUniversity of Oxford · GBKazan Federal University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The GluA1 subunit of the L-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) plays a crucial, but highly selective, role in cognitive function. Here we analyzed AMPAR expression, AMPAR distribution and spatial learning in mice (

Indexed as

AMPA receptorsGluA1long-term potentiationMorris water-mazeRNA-editingspatial memoryspatial working memory

Identifiers

PMID29988555
PMCPMC6026654
OpenAlexW2810581962

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.