Evidence map›Paper›PMID 29988464›Full record

ArticleWorld journal of emergency surgery : WJES2018

Should ambulatory appendectomy become the standard treatment for acute appendicitis?

Benoit Gignoux, Marie-Cecile Blanchet, Thomas Lanz, Alexandre Vulliez, Mo Saffarini, Hugo Bothorel, Maud Robert, Vincent Frering

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in World journal of emergency surgery : WJES, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07401407 (APENERAS), which is not on this map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07401407 completednot on this mapstarted 2022, after this paper: background citation

APENERAS: A Prospective Multicenter Observational Study of RICA (ERAS) Pathway Adherence, Safety Outcomes, and Early Discharge Feasibility in Adults Undergoing Urgent Uncomplicated Appendectomy

TypeobservationalSponsorHospital Galdakao-UsansoloRan2022 to 2025Enrolled193ConditionsAcute Appendicitis, Appendectomy, Ambulatory Surgery
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 3 countries.

Benoit GignouxDepartment of General, Visceral and Endocrine Surgery, Clinique de la Sauvegarde, Lyon, France.
Marie-Cecile BlanchetDepartment of General, Visceral and Endocrine Surgery, Clinique de la Sauvegarde, Lyon, France.
Thomas LanzDepartment of Anesthesiology, Clinique de la Sauvegarde, Lyon, France.
Alexandre VulliezDepartment of Anesthesiology, Clinique de la Sauvegarde, Lyon, France.
Mo SaffariniMedical Technology, ReSurg SA, ch. de la Vuarpilliere 35, 1260 Nyon, Switzerland.ORCID 0000-0002-9656-987X
Hugo BothorelMedical Technology, ReSurg SA, ch. de la Vuarpilliere 35, 1260 Nyon, Switzerland.
Maud Robert4Department of Digestive Surgery, University Hospital Edouard Herriot, Lyon, France.
Vincent FreringDepartment of General, Visceral and Endocrine Surgery, Clinique de la Sauvegarde, Lyon, France.
Santhera Pharmaceuticals (Switzerland) · CHHôpital Edouard Herriot · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Appendectomy is increasingly performed as a 'short stay' or 'ambulatory' procedure, yet there is no consensus for selection of patients with acute appendicitis for ambulatory surgery (AS). We aimed to compare characteristics and outcomes of complicated and uncomplicated appendectomies performed in ambulatory vs. conventional settings, and to determine factors associated with unexpected re-consultations and re-hospitalizations. Methods: The authors reviewed a consecutive series of 185 laparoscopic appendectomies. Whenever possible, patients were offered AS, defined as 'discharge on the same working day.' Multivariable regressions were performed to determine associations of unexpected re-consultations and re-hospitalizations with surgery type (ambulatory or conventional) and patient characteristics (age, gender, obesity, symptoms, appendicolith, perforations, appendix diameter, serologic results, American Society of Anesthesiologists score, and Saint-Antoine score). Results: From the initial cohort, 117 patients (63.2%) were eligible for AS, of which 8 had peri- or post-operative contraindications. Therefore, 109 patients (58.9%) were operated by AS, with median length of stay 8.5 h (range, 3.3-20.5). Ambulatory cases had a lower incidence of complications (11.9%) than conventional cases (25.0%) ( Conclusions: Ambulatory surgery could be considered as a standard procedure for both complicated and uncomplicated acute appendicitis. Appendicolith was found to be an independent risk factor for unexpected re-hospitalization and should therefore trigger closer monitoring.

Indexed as

Time FactorsAcute DiseaseAdolescentAdultAgedAged, 80 and overAmbulatory Surgical ProceduresAppendectomyAppendicitisAppendixChildFemaleHumansLaparoscopyMaleMiddle AgedAmbulatory surgeryAppendicolithComplicated appendicitisConventional hospitalizationLaparascopic appendectomy

Identifiers

PMID29988464
PMCPMC6025707
OpenAlexW2810388273

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.