Evidence map›Paper›PMID 29988381›Full record

ArticleFrontiers in immunology2018

Anti-Allergic Inflammatory Activity of Interleukin-37 Is Mediated by Novel Signaling Cascades in Human Eosinophils.

Jing Zhu, Jie Dong, Lu Ji, Peiyong Jiang, Ting Fan Leung, Dehua Liu, Lai Guan Ng, Miranda Sin-Man Tsang, Delong Jiao, Christopher Wai-Kei Lam and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 30 citations in OpenAlex.

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  15. Exosomes: an important messenger in the asthma inflammatory microenvironment.The Journal of international medical research · 2020
    Article
  16. Article
  17. Inhalation of nebulizedAllergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2020
    Article
  18. Article
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 4 countries.

Jing ZhuDepartment of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, Hong Kong.
Jie DongDepartment of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, Hong Kong.
Lu JiDepartment of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, Hong Kong.
Peiyong JiangDepartment of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, Hong Kong.
Ting Fan LeungDepartment of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, Hong Kong.
Dehua LiuInstitute of Chinese Medicine, State Key Laboratory of Phytochemistry and Plant Resources in West China, The Chinese University of Hong Kong, Hong Kong, Hong Kong.
Lai Guan NgSingapore Immunology Network, Singapore, Singapore.
Miranda Sin-Man TsangInstitute of Chinese Medicine, State Key Laboratory of Phytochemistry and Plant Resources in West China, The Chinese University of Hong Kong, Hong Kong, Hong Kong.
Delong JiaoDepartment of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, Hong Kong.
Christopher Wai-Kei LamState Key Laboratory of Quality Research in Chinese Medicines, Macau Institute for Applied Research in Medicine and Health, Macau University of Science and Technology, Taipa, Macau.
Chun-Kwok WongDepartment of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, Hong Kong.
Chinese University of Hong Kong · CNPrince of Wales Hospital · CNQuality Research · USSingapore Immunology Network · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IL-1 family regulatory cytokine IL-37b can suppress innate immunity and inflammatory activity in inflammatory diseases. In this study, IL-37b showed remarkable

Indexed as

allergic asthmaeosinophilsinterleukin-37signal transductiontranscriptional profile

Identifiers

PMID29988381
PMCPMC6023969
OpenAlexW2808390096

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.