Evidence map›Paper›PMID 29988221›Full record

ArticleEuropean journal of dentistry

Effect of heat treatment on cytotoxicity of self-adhesive resin cements: Cell viability analysis.

Celso Afonso Klein-Júnior, Roberto Zimmer, Guilherme Scotta Hentschke, Denise Cantarelli Machado, Rubem Beraldo Dos Santos, Eduardo Galia Reston

Open access · hybridAbstract read
In one paragraph

Article in European journal of dentistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.9field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 27 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Cytotoxicity assessment of Bio-C Repair Íon+: A new calcium silicate-based cement.Journal of dental research, dental clinics, dental prospects · 2021
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Celso Afonso Klein-JúniorDepartment of Operative Dentistry, School of Dentistry, Lutheran University of Brazil, Cachoeira do Sul, Rio Grande do Sul, Brazil.
Roberto ZimmerDepartment of Operative Dentistry, School of Dentistry, Lutheran University of Brazil, Cachoeira do Sul, Rio Grande do Sul, Brazil.
Guilherme Scotta HentschkeDepartment of Cell Biology, Lutheran University of Brazil, Cachoeira do Sul, Rio Grande do Sul, Brazil.
Denise Cantarelli MachadoNeuroscience Department, Brain Institute, Neuroscience Laboratory, Pontifical Catholic University of Rio Grande do Sul, Rio Grande do Sul, Brazil.
Rubem Beraldo Dos SantosDepartment of Operative Dentistry, School of Dentistry, Lutheran University of Brazil, Cachoeira do Sul, Rio Grande do Sul, Brazil.
Eduardo Galia RestonDepartment of Operative Dentistry, School of Dentistry, Lutheran University of Brazil, Cachoeira do Sul, Rio Grande do Sul, Brazil.
Universidade Luterana do Brasil · BRPontifícia Universidade Católica do Rio Grande do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of the study was to assess,

methodsSamples were divided into three groups: (1) no heat treatment while mixing (control), (2) 37°C, and (3) 60°C heat treatment while mixing. Cements were light-cured immediately after mixing and immersed in Dulbecco's Modified Eagle Media for the extraction of possibly uncured products after 24 h and 7 days. Cultures contained 0.5 mL of NIH/3T3 fibroblasts per well at a concentration of 0.4 × 10 STATISTICAL ANALYSIS USED: Data were statistically analyzed with ANOVA and

resultsCement cytotoxicity increased with time, as shown by the higher values observed at 7 days. There was a slight difference in intragroup cytotoxicity levels between 24 h and 7 days. Heat treatment at 60°C was associated with a major decrease in cytotoxicity levels in all three groups, both at 24 h and at 7 days, with no differences among the cements.

conclusionsHeat treatment at 60°C should be considered as a strategy to reduce cytotoxicity of self-adhesive resin cements, as evidenced by the results observed at 24 h and 7 days of analysis.

Indexed as

Biocompatibilitydental materialstoxic substances

Identifiers

PMID29988221
PMCPMC6004809
OpenAlexW2807403561

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.