Superfast DNA replication causes damage in cancer cells.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

11 citing papers in PubMed.

1. Replication stress responses in human lymphocytes change sex-specifically during aging.Nucleic acids research · 2025
   Article
2. Structural and functional insights into the epigenetic regulator MRG15.Acta pharmacologica Sinica · 2024
   Review
3. Leveraging the replication stress response to optimize cancer therapy.Nature reviews. Cancer · 2023
   Review
4. Distinct signaling signatures drive compensatory proliferation via S-phase acceleration.PLoS genetics · 2022
   Article
5. The potential of PARP inhibitors in targeted cancer therapy and immunotherapy.Frontiers in molecular biosciences · 2022
   Review
6. Structural Insight into the Mechanism of PALB2 Interaction with MRG15.Genes · 2021
   Article
7. A novel cell-cycle-regulated interaction of the Bloom syndrome helicase BLM with Mcm6 controls replication-linked processes.Nucleic acids research · 2021
   Article
8. Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency.Molecular cell · 2021
   Article
9. Structural and functional studies of SF1B Pif1 from Thermus oshimai reveal dimerization-induced helicase inhibition.Nucleic acids research · 2021
   Article
10. Nuclear PARPs and genome integrity.Genes & development · 2020
    Review
11. PARP Inhibitors: Clinical Relevance, Mechanisms of Action and Tumor Resistance.Frontiers in cell and developmental biology · 2020
    Review

Corrections and comments

• Comment on
  High speed of fork progression induces DNA replication stress and genomic instability.2018

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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