Evidence map›Paper›PMID 29987984›Full record

ArticleThe British journal of radiology2018

Mandibular indexes and fractal properties on the panoramic radiographs of the patients using aromatase inhibitors.

Duygu Göller Bulut, Seval Bayrak, Ummügül Uyeturk, Handan Ankarali

Open access · greenAbstract read
In one paragraph

Article in The British journal of radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Duygu Göller Bulut1 Department of Dentomaxillofacial Radiology, Abant Izzet Baysal University, Faculty of Dentistry , Bolu , Turkey.
Seval Bayrak1 Department of Dentomaxillofacial Radiology, Abant Izzet Baysal University, Faculty of Dentistry , Bolu , Turkey.
Ummügül Uyeturk2 Department of Medical Oncology, Abant Izzet Baysal University, Faculty of Medicine , Bolu , Turkey.
Handan Ankarali3 Biostatistics and Medical Informatics Department, Istanbul Medeniyet University, Faculty of Medicine , Istanbul , Turkey.
Bolu Abant İzzet Baysal University · TRIstanbul Medeniyet University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objective: This study was conducted to evaluate fractal dimension (FD), mandibular cortical width (MCW), panoramic mandibular index (PMI), and mandibular cortical index (MCI) on panoramic radiographs to determine the mandibular cortical and trabecular bone changes in females with breast cancer undergoing aromatase inhibitors (AIs) treatment.

methods: In this retrospective study, FD analysis, PMI, MCI, and MCW were assessed over panoramic radiographs of 34 females under AI therapy as a patient group and 34 healthy age-gender matched individuals as a control group.

results: Mean FD values and MCW were slightly but not significantly lower in the patient group (1.47 ± 0.06 and 4.1 ± 1.2 respectively). FDs measured onthe supracortical area above the angulus mandibula (FD2) and anterior to the mental foramen (FD4) were significantly lower in patients (p = 0.037 and p = 0.046 respectively). Among the measured regions in patients, FD2 was significantly lower (p = 0.001). PMI was also significantly lower in patients (p = 0.001) and MCI were similar in both groups (p = 0.604).

conclusion: AI use affects bone quality and evaluating FD, PMI, and MCW in panoramic radiography can be used to determine the effect of this drug on the jaw bones in the early period. ADVANCES IN KNOWLEDGE:: Aromatase inhibitors are the most commonly used drugs in breast cancer patients. This drug is thought to have osteoporotic effects on the jawbone. This study is the first study to evaluate osteoporotic changes with measurements made on panoramic radiographs and the results of the study are significant. We think this study will shed light on the studies that will investigate the effects of the drug on the jaw bones.

Indexed as

Antineoplastic AgentsAromatase InhibitorsBone DensityBreast NeoplasmsCancellous BoneCase-Control StudiesFemaleFractalsHumansMandibleRadiography, PanoramicRetrospective StudiesAntineoplastic AgentsAromatase Inhibitors

Identifiers

PMID29987984
PMCPMC6475946
OpenAlexW2821413605

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.