Evidence map›Paper›PMID 29987921›Full record

ArticleMicrobiologyOpen2019

Prevalence and characterization of carbapenem-resistant bacteria in water bodies in the Los Angeles-Southern California area.

Dana E Harmon, Osvaldo A Miranda, Ashley McCarley, Michelle Eshaghian, Natasha Carlson, Cristian Ruiz

Abstract read
In one paragraph

Article in MicrobiologyOpen, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Review
  2. Carbapenem-resistant bacteria in the environment.Arhiv za higijenu rada i toksikologiju · 2025
    Review
  3. Review
  4. Severe pneumonia due toFrontiers in medicine · 2025
    Article
  5. Review
  6. Article
  7. Genomic Sequencing of ClinicalInfection and drug resistance · 2024
    Article
  8. Article
  9. Molecular epidemiology and genomic characterization of a plasmid-mediatedComputational and structural biotechnology journal · 2023
    Article
  10. Review
  11. Article
  12. High Frequency of Antibiotic Resistance Genes (ARGs) in the Lerma River Basin, Mexico.International journal of environmental research and public health · 2022
    Article
  13. Antibiotics (Basel, Switzerland) · 2022
    Review
  14. Article
  15. KPC-3-, GES-5-, and VIM-1-ProducingInternational journal of environmental research and public health · 2022
    Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dana E HarmonDepartment of Biology, California State University Northridge, Northridge, California.
Osvaldo A MirandaDepartment of Biology, California State University Northridge, Northridge, California.
Ashley McCarleyDepartment of Biology, California State University Northridge, Northridge, California.
Michelle EshaghianDepartment of Biology, California State University Northridge, Northridge, California.
Natasha CarlsonDepartment of Biology, California State University Northridge, Northridge, California.
Cristian RuizDepartment of Biology, California State University Northridge, Northridge, California.ORCID 0000-0003-0039-5180

Funding

BUILD PODER IITL4GM118977 · NIGMS · CALIFORNIA STATE UNIVERSITY NORTHRIDGE · PI CHAVIRA, GABRIELA, KHACHIKIAN, CRIST SIMON · 2015 to 2023
$18.1M
BUILD PODER IIRL5GM118975 · NIGMS · CALIFORNIA STATE UNIVERSITY NORTHRIDGE · PI CHAVIRA, GABRIELA, KHACHIKIAN, CRIST SIMON · 2015 to 2023
$10.7M
Project-002UL1GM118976 · NIGMS · CALIFORNIA STATE UNIVERSITY NORTHRIDGE · PI SAETERMOE, CARRIE L · 2015 to 2023
$7.8M
NIGMS NIH HHS RL5 GM118975NIGMS NIH HHS TL4 GM118977NIGMS NIH HHS UL1 GM118976
6 · The paper itself

Abstract

Carbapenems are β-lactam antibiotics used in healthcare settings as last resort drugs to treat infections caused by antibiotic-resistant bacteria. Carbapenem-resistant bacteria are increasingly being isolated from healthcare facilities; however, little is known about their distribution or prevalence in the environment, especially in the United States, where their distribution in water environments from the West Coast has not been studied before. The aim of this study was to determine the prevalence of carbapenem-resistant bacteria and carbapenemase genes in water bodies from the Los Angeles area (California, USA). All samples that were analyzed contained carbapenem-resistant bacteria with a frequency of between 0.1 and 324 carbapenem-resistant cfu per 100 mls of water. We identified 76 carbapenem-resistant or -intermediate isolates, most of which were also resistant to noncarbapenem antibiotics, as different strains of Enterobacter asburiae, Aeromonas veronii, Cupriavidus gilardii, Pseudomonas, and Stenotrophomonas species. Of them, 52 isolates were carbapenemase-producers. Furthermore, PCR and sequence analysis to identify the carbapenemase gene of these carbapenemase-producing isolates revealed that all Enterobacter asburiae isolates had a bla

Indexed as

Drug Resistance, BacterialAnti-Bacterial AgentsBacteriaBacterial Proteinsbeta-LactamasesCarbapenemsFresh WaterLos AngelesMicrobial Sensitivity TestsPrevalenceAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasescarbapenemaseCarbapenemsAeromonascarbapenemcarbapenemasecarbapenem-resistantCupriavidusEnterobacterPseudomonasStenotrophomonas

Identifiers

PMID29987921
PMCPMC6460273

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.