Evidence map›Paper›PMID 29987750›Full record

ArticleIndian journal of gastroenterology : official journal of the Indian Society of Gastroenterology2018

Risk factors for inflammatory bowel disease: A prospective multi-center study.

Anjali D Amarapurkar, Deepak N Amarapurkar, Pravin Rathi, Prabha Sawant, Nikhil Patel, Praful Kamani, Krishnakant Rawal, Rajiv Baijal, Ameya Sonawane, Nitin Narawane and 2 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

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  6. Inflammatory bowel disease in south Asia: a scoping review.The lancet. Gastroenterology & hepatology · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Anjali D AmarapurkarDepartment of Pathology, Topiwala National Medical College and B Y L Nair Charitable Hospital, Mumbai, 400 008, India. anjali1963@gmail.com.
Deepak N AmarapurkarDepartment of Gastroenterology and Hepatology, Bombay Hospital, New Marine Lines, Mumbai, 400 020, India.
Pravin RathiDepartment of Gastroenterology, Topiwala National Medical College and B Y L Nair Charitable Hospital, Mumbai, 400 008, India.
Prabha SawantDepartment of Gastroenterology, Lokmanya Tilak Municipal Medical College and Sion Hospital, Mumbai, 400 022, India.
Nikhil PatelDepartment of Gastroenterology, Jeevandeep Hospital, Anand, 388 001, India.
Praful KamaniDepartment of Gastroenterology, Wockhardt Hospital, Rajkot, 360 007, India.
Krishnakant RawalDepartment of Gastroenterology and Liver Disease, Milestone Hospital, Rajkot, 360 002, India.
Rajiv BaijalDepartment of Gastroenterology, Jagjivan Ram Western Railway Hospital, Mumbai, 400 008, India.
Ameya SonawaneDepartment of Gastroenterology and Hepatology, Bombay Hospital, New Marine Lines, Mumbai, 400 020, India.
Nitin NarawaneLake City Endoscopy Centre, Thane, 400 602, India.
Samrat KolekarDepartment of Pathology, Topiwala National Medical College and B Y L Nair Charitable Hospital, Mumbai, 400 008, India.
Naveen TotlaDepartment of Gastroenterology, Jagjivan Ram Western Railway Hospital, Mumbai, 400 008, India.
Topiwala National Medical College & BYL Nair Charitable Hospital · INBombay Hospital · INSouth Eastern Railway · INGreat Lakes Institute of Management · INLokmanya Tilak Municipal General Hospital and Lokmanya Tilak Municipal Medical College · INWockhardt Hospitals · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionEnvironmental risk factors have been associated with inflammatory bowel disease (IBD). With rising incidence, it is important to know risk factors associated with IBD in our population. This study was aimed to evaluate risk factors for IBD from western India.

methodsThis was prospective, multi-center case-control study which included 1054 patients with IBD of which 765 (72.5%) were ulcerative colitis (UC) and 289 (27.4%) Crohn's disease (CD). Asymptomatic individuals without a history of any major illness served as controls. The questionnaire containing risk factors for IBD was given to patients and control group. Odds ratio and 95% confidence interval were calculated for each variable.

resultSignificant numbers of patients with CD were from rural area. Rural environment (OR 1.071, 0.82-1.38 and OR 1.441, 1.02-2.02), higher education (OR 1.830, 1.52-2.19 and OR 1.519, 1.16-1.97), professional by occupation (OR 1.754, 1.46-2.09 and OR 1.293, 0.99-1.67), annual family income >100,000 Indian national rupees (OR 2.185, 1.52-3.13 and OR 4.648, 3.10-6.95), history of appendectomy (OR 3.158, 1.71-5.80 and OR 3.158, 1.71-5.80), and family history of IBD (OR 4.510, 2.19-9.25 and OR 3.972, 1.58-9.96) were the risk factors for UC and CD, respectively. Vegetarian diet was protective factor for UC (OR 0.29, 0.27-0.39) and risk for CD (OR 1.179, 0.88-1.57). Smoking and chronic alcoholism were not found to be the risk factors.

conclusionThis study highlights association between socioeconomic, dietary factors, appendectomy, and family history as risk factors for IBD.

Indexed as

AppendectomyCase-Control StudiesColitis, UlcerativeConfidence IntervalsCrohn DiseaseDiet, VeganEducational StatusEnvironmentFemaleHumansIncomeIndiaMaleOccupationsOdds RatioProspective StudiesCrohn’s diseaseExtraintestinal manifestationsUlcerative colitis

Identifiers

PMID29987750
OpenAlexW2868233831

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.