ReviewCurrent reviews in musculoskeletal medicine2018
The Role of One-Stage Exchange for Prosthetic Joint Infection.
Review in Current reviews in musculoskeletal medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 77 citations in OpenAlex.
- Reinfection rates after one- and two-stage revision surgery for hip and knee arthroplasty: a systematic review and meta-analysis.Archives of orthopaedic and trauma surgery · 2023Pooled it
- One- vs. Two-Stage Exchange for Chronic Hip Periprosthetic Joint Infection: A Framework Based on Patient Treatment Burden and Institutional Capability.JBJS reviews · 2026Review
- The burden of care in hip and knee prosthetic joint infections (PJI) in a regional unit.Irish journal of medical science · 2026Article
- Osteomyelitis in peri-implant bone of hip prosthetic joint infection: prevalence and clinical impact.Journal of bone and joint infection · 2026Article
- Periprosthetic joint infection after arthroplasty: advances and future prospects.Journal of orthopaedic surgery and research · 2025Review
- A Single Tertiary-Care Center Case Series Using Vertical Rectus Abdominis Myocutaneous Flap in the Management of Complex Periprosthetic Joint Infection of the Hip.Microorganisms · 2025Article
- One- versus two-stage septic hip and knee revision surgery: a comparative cohort outcome study with short- to mid-term follow-up.Journal of bone and joint infection · 2025Article
- Variations in clinical practice of one-stage septic revisions in chronic hip and knee periprosthetic joint infections: an international questionnaire study.Archives of orthopaedic and trauma surgery · 2024Article
- Review of recent advances in the diagnosis and management of periprosthetic joint infection after total knee arthroplasty part 2: single-stage or two-stage surgical technique?Journal of orthopaedic surgery and research · 2024Review
- Antibiotic-Loaded Hydrogel for the Treatment of Lower-Limb Fracture-Related Infections: A Single Center's Multidisciplinary Experience.Gels (Basel, Switzerland) · 2024Article
- Do one-stage indications predict success following two-stage arthroplasty for chronic periprosthetic joint infection?Journal of bone and joint infection · 2024Article
- Outcomes ofClinics in orthopedic surgery · 2023Article
- Periprosthetic knee infection in octogenarians: a single institution experience at midterm outcome.Archives of orthopaedic and trauma surgery · 2023Article
- Is a preoperative pathogen detection a prerequisite before undergoing one-stage exchange for prosthetic joint infection of the hip?Archives of orthopaedic and trauma surgery · 2023Article
- Prosthetic Joint Infections: Biofilm Formation, Management, and the Potential of Mesoporous Bioactive Glass as a New Treatment Option.Pharmaceutics · 2023Review
- Piperacillin Steady State Concentrations in Target Tissues Relevant for PJI Treatment-A Randomized Porcine Microdialysis Study Comparing Continuous Infusion with Intermittent Short-Term Infusion.Antibiotics (Basel, Switzerland) · 2023Article
- Poor outcome after debridement and implant retention for acute hematogenous periprosthetic joint infection: a cohort study of 43 patients.Acta orthopaedica · 2023Article
- 'Tis Time 'Tis Time: The Importance of Operative Time, Thoroughness, and Shakespeare in Dair Procedures in Total Joint Arthroplasty.The Iowa orthopaedic journal · 2023Article
- Periprosthetic Knee Infection - Part 2: Treatment.Revista brasileira de ortopedia · 2022Article
- Two stage revision: indications, techniques and results.Annals of joint · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewIn an era of increasing numbers of hip and knee replacements, strategies to manage prosthetic joint infection (PJI) that are effective at infection control with good patient-reported outcomes and cost containment for health systems are needed. Interest in single-stage exchange for PJI is rising and we assess evidence from the last 5 years related to this treatment strategy. RECENT
findingsOnly five series for total knee replacement and ten series for total hip replacement have been reported in the last five years. More review articles and opinion pieces have been written. Reinfection rates in these recent studies range from 0 to 65%, but a meta-analysis and systematic review of all studies showed a reinfection rate of 7.6% (95% CI 3.4-13.1) and 8.8% (95% CI 7.2-10.6) for single-stage and two-stage revisions respectively. There is emerging evidence to support single-stage revision in the setting of significant bony deficiency and atypical PJIs such as fungal infections. Prospective randomised studies are recruiting and are necessary to guide the direction of single-stage revision selection criteria. The onus of surgical excellence in mechanical removal of implants, necrotic tissue, and biofilms lies with the arthroplasty surgeon and must remain the cornerstone of treatment. Single-stage revision may be considered the first-line treatment for all PJIs unless the organism is unknown, the patient is systemically septic, or there is a poor tissue envelope.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.