Evidence map›Paper›PMID 29987623›Full record

ReviewCurrent cardiology reports2018

Coronary Artery Calcium Score: the "Mammogram" of the Heart?

Miguel Cainzos-Achirica, Philip A Di Carlo, Catherine E Handy, Renato Quispe, Gerard Roura, Xavier Pinto, Roger S Blumenthal, Josep Comin-Colet, Xavier Corbella, Michael J Blaha

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current cardiology reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Miguel Cainzos-AchiricaJohns Hopkins Ciccarone Center for the Prevention of Cardiovascular Disease, Johns Hopkins Medical Institutions, Baltimore, MD, USA. mcainzos@bellvitgehospital.cat.
Philip A Di CarloBreast Imaging Division, The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, Baltimore, MD, USA.
Catherine E HandyJohns Hopkins Ciccarone Center for the Prevention of Cardiovascular Disease, Johns Hopkins Medical Institutions, Baltimore, MD, USA.
Renato QuispeJohns Hopkins Ciccarone Center for the Prevention of Cardiovascular Disease, Johns Hopkins Medical Institutions, Baltimore, MD, USA.
Gerard RouraDepartment of Cardiology, Bellvitge University Hospital and Bellvitge Biomedical Research Institute (IDIBELL), 19th Floor, Feixa Llarga s/n, 08907 L'Hospitalet de Llobregat, Barcelona, Spain.
Xavier PintoCardiovascular Risk Unit, Department of Internal Medicine, Bellvitge University Hospital, 7th Floor, Feixa Llarga s/n, 08907 L'Hospitalet de Llobregat, Barcelona, Spain.
Roger S BlumenthalJohns Hopkins Ciccarone Center for the Prevention of Cardiovascular Disease, Johns Hopkins Medical Institutions, Baltimore, MD, USA.
Josep Comin-ColetDepartment of Cardiology, Bellvitge University Hospital and Bellvitge Biomedical Research Institute (IDIBELL), 19th Floor, Feixa Llarga s/n, 08907 L'Hospitalet de Llobregat, Barcelona, Spain.
Xavier CorbellaCardiovascular Risk Unit, Department of Internal Medicine, Bellvitge University Hospital, 7th Floor, Feixa Llarga s/n, 08907 L'Hospitalet de Llobregat, Barcelona, Spain.
Michael J BlahaJohns Hopkins Ciccarone Center for the Prevention of Cardiovascular Disease, Johns Hopkins Medical Institutions, Baltimore, MD, USA.
Johns Hopkins University · USBellvitge University Hospital · ESInstitut d'Investigació Biomédica de Bellvitge · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewTo discuss the classic analogy of "coronary artery calcium (CAC) as a mammogram of the heart", by evaluating the conceptual strengths, weaknesses, opportunities, and threats of a potential cardiovascular disease (CVD) screening strategy using CAC in apparently healthy adults. RECENT

findingsCAC is typically used for further CVD risk assessment. CAC is also currently being used as a screening test in specific subgroups of individuals, particularly in some Asian countries. Although this has yielded valuable insights on the determinants and pathophysiology of CVD, whether this approach results in improved clinical outcomes compared to other assessment and management approaches is currently unclear. Although CAC and mammograms share a number of characteristics, there are also important conceptual differences. The evidence supporting CAC, which is a robust CVD risk assessment tool, for CVD screening purposes is currently very limited, and further research is needed.

Indexed as

CalciumCardiovascular DiseasesCoronary VesselsHumansMass ScreeningPredictive Value of TestsRiskTomography, X-Ray ComputedCalciumAtherosclerosisCardiovascular diseaseCoronary artery calciumMammogramRisk assessmentScreening

Identifiers

PMID29987623
OpenAlexW2816420334

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.