Evidence map›Paper›PMID 29987617›Full record

ArticleMolecular imaging and biology2019

How Long of a Dynamic 3'-Deoxy-3'-[

Jun Zhang, Xiaoli Liu, Michelle I Knopp, Bhuvaneswari Ramaswamy, Michael V Knopp

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular imaging and biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Observational
  2. Article
  3. Dual time point [EJNMMI research · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jun ZhangWright Center of Innovation in Biomedical Imaging, Department of Radiology, The Ohio State University Wexner Medical Center, 395 W. 12th Avenue, Room 430, Columbus, OH, 43210-1228, USA.
Xiaoli LiuWright Center of Innovation in Biomedical Imaging, Department of Radiology, The Ohio State University Wexner Medical Center, 395 W. 12th Avenue, Room 430, Columbus, OH, 43210-1228, USA.
Michelle I KnoppWright Center of Innovation in Biomedical Imaging, Department of Radiology, The Ohio State University Wexner Medical Center, 395 W. 12th Avenue, Room 430, Columbus, OH, 43210-1228, USA.
Bhuvaneswari RamaswamyDepartment of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, 43210, USA.
Michael V KnoppWright Center of Innovation in Biomedical Imaging, Department of Radiology, The Ohio State University Wexner Medical Center, 395 W. 12th Avenue, Room 430, Columbus, OH, 43210-1228, USA. knopp.16@osu.edu.ORCID http://orcid.org/0000-0001-9543-2962
The Ohio State University Wexner Medical Center · US

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Tasleem J Padamsee · 1985 to 2026
$132.3M
IROC: Enhancing local enrolling site radiological data capture capabilities for NCTN trialsU24CA180803 · NCI · AMERICAN COLLEGE OF RADIOLOGY · PI Thomas J. FitzGerald, MICHAEL V KNOPP · 2014 to 2026
$116.2M
UM1 Supplement for Early Therapeutic Trials with Phase 2 IntentUM1CA186712 · NCI · OHIO STATE UNIVERSITY · PI SUSANNE M ARNOLD, WILLIAM E. CARSON · 2014 to 2026
$19.3M
PHASE I TRIALS OF ANTICANCER AGENTSU01CA076576 · NCI · OHIO STATE UNIVERSITY · PI GREVER, MICHAEL R · 1998 to 2013
$9.1M
NCI NIH HHS P30 CA016058NCI NIH HHS U01 CA076576NCI NIH HHS U24 CA180803NCI NIH HHS UM1 CA186712
6 · The paper itself

Abstract

purposeTo quantitatively evaluate the minimally required scanning time of 3'-deoxy-3'-[ PROCEDURES: Within a therapeutic intervention trial, 26 breast tumors of 8 breast cancer patients were analyzed from 30-min dynamic [

resultsThe correlation of kinetic parameters between the gold standard and the abbreviated dynamic data series increased with longer T

conclusionsThis study indicates that a 16-min dynamic PET acquisition appears to be sufficient to provide accurate [

Indexed as

Positron-Emission TomographyBreast NeoplasmsDideoxynucleosidesFemaleFluorine RadioisotopesHumansKineticsMiddle AgedSignal-To-Noise Ratio3',3'-difluoro-3'-deoxythymidineDideoxynucleosidesFluorine-18Fluorine Radioisotopes3′-Deoxy-3′-[18F]fluorothymidine ([18F]FLT)Acquisition durationBreast CancerDynamic PETKinetic modeling

Identifiers

PMID29987617
PMCPMC7201384
OpenAlexW2817523459

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.