Trial reportSurgical endoscopy2019
Enhanced recovery after surgery protocol allows ambulatory laparoscopic appendectomy in uncomplicated acute appendicitis: a prospective, randomized trial.
Trial report in Surgical endoscopy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 24 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Safety and Efficacy of Enhanced Recovery After Surgery Therapeutic Protocol for Complicated Appendicitis in Children
APENERAS: A Prospective Multicenter Observational Study of RICA (ERAS) Pathway Adherence, Safety Outcomes, and Early Discharge Feasibility in Adults Undergoing Urgent Uncomplicated Appendectomy
Who cites it
24 citing papers in PubMed, 6 syntheses or guidelines pooled it, 54 citations in OpenAlex.
- Swedish national guidelines for diagnosis and management of acute appendicitis in adults and children.BJS open · 2025Guideline
- Enhanced Recovery After Surgery Guidelines and Hospital Length of Stay, Readmission, Complications, and Mortality: A Meta-Analysis of Randomized Clinical Trials.JAMA network open · 2024Pooled it
- Impact of enhanced recovery pathways on patient-reported outcomes after abdominal surgery: a systematic review.Surgical endoscopy · 2023Pooled it
- Feasibility of Same-Day Discharge After Appendectomy in Pediatric Patients: A Systematic Review and Meta-Analysis.Frontiers in pediatrics · 2022Pooled it
- Same-day discharge after appendectomy for acute appendicitis: a systematic review and meta-analysis.International journal of colorectal disease · 2021Pooled it
- Ambulatory versus conventional laparoscopic appendectomy: a systematic review and meta-analysis.International journal of colorectal disease · 2019Pooled it
- Outpatient management of acute uncomplicated appendicitis after laparoscopic appendectomy: a randomized controlled trial.World journal of emergency surgery : WJES · 2022Trial
- Enhanced Recovery After Surgery (ERAS) in Latin America and the Caribbean: A Scoping Review of Implementation Strategies, Clinical Outcomes, and Health System Impact.World journal of surgery · 2026Article
- Outcomes and Safety of Same-Day Discharge Following Minimally Invasive Abdominal Surgery: A Systematic Review.Cureus · 2026Review
- Article
- PACU discharge: equally safe and more cost-effective than floor admission for uncomplicated laparoscopic appendectomy.Perioperative medicine (London, England) · 2025Article
- Same-day discharge for laparoscopic Heller myotomy.Surgical endoscopy · 2022Article
- Single-port laparoscopic appendectomy using a needle-type grasping forceps compared with conventional three-port laparoscopic appendectomy for patients with acute uncomplicated appendicitis: a single-center retrospective study.The Journal of international medical research · 2022Article
- Single-port laparoscopic appendectomy using a needle-type grasping forceps for selective adult patients with acute uncomplicated appendicitis.Journal of surgical case reports · 2022Article
- Quality of recovery assessment of day case and multiday stay patients undergoing elective laparoscopic cholecystectomy.Turkish journal of surgery · 2021Article
- Systematic review and meta-analysis of the effects of the perioperative enhanced recovery after surgery concept on the surgical treatment of acute appendicitis in children.Translational pediatrics · 2021Article
- Implementation of an Enhanced Recovery After Surgery (ERAS) protocol for acute complicated and uncomplicated appendicitis.Techniques in coloproctology · 2021Article
- Comparing the Postoperative Outcomes of Single-Incision Laparoscopic Appendectomy and Three Port Appendectomy With Enhanced Recovery After Surgery Protocol for Acute Appendicitis: A Propensity Score Matching Analysis.Annals of coloproctology · 2021Article
- Surgical rectus sheath block combined with multimodal pain management reduces postoperative pain and analgesic requirement after single-incision laparoscopic appendectomy: a retrospective study.International journal of colorectal disease · 2021Article
- Risk Factors for Readmission After Short-Hospital-Stay Laparoscopic Appendectomy.World journal of surgery · 2020Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrevious observational studies have demonstrated the safety of discharging patients after laparoscopic appendectomy within the same day without hospitalization. The application of Enhanced Recovery After Surgery (ERAS) guidelines has resulted in shorter length of stay, fewer complications, and reduction in medical costs. The aim of this study was to investigate if ERAS protocol implementation in patients with acute uncomplicated appendicitis decreases the length of stay enough to allow for ambulatory laparoscopic appendectomy.
methodsIn this prospective, randomized controlled clinical trial, 108 patients were randomized into two groups: laparoscopic appendectomy with ERAS (LA-E) or laparoscopic appendectomy with conventional care (LA-C). The primary endpoint was postoperative length of stay. The secondary end points were time to resume diet, postoperative pain, postoperative complications, re-admission rate, and reoperation rate.
resultsFrom January 2016 through May 2017, 50 patients in the LA-E group and 58 in the LA-C were analyzed. There were no significant differences in preoperative data. Regarding the primary end point of the study, the ERAS protocol significantly reduced the postoperative length of stay with a mean of 9.7 h (SD: 3.1) versus 23.2 h (SD: 6.8) in the conventional group (p < 0.001). The ERAS protocol allowed ambulatory management in 90% of the patients included in this group. There was a significant reduction in time to resume diet (110 vs. 360 min, p < 0.001) and less moderate-severe postoperative pain (28 vs. 62.1%, p < 0.001) in the LA-E versus LA-C group. The rate of complications, readmissions, and reoperations were comparable in both groups (p = 0.772).
conclusionsERAS implementation was associated with a significantly shorter length of stay, allowing for the ambulatory management of this group of patients. Ambulatory laparoscopic appendectomy is safe and feasible with similar rates of morbidity and readmissions compared with conventional care.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.