Evidence map›Paper›PMID 29987341›Full record

ArticleStrahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]2018

Pattern of dysphagia after swallowing-sparing intensity-modulated radiotherapy (IMRT) of head and neck cancers: results of a mono-institutional prospective study.

Stefano Ursino, Paola Cocuzza, Veronica Seccia, Durim Delishaj, Agostino Cristaudo, Francesco Pasqualetti, Patrizia Giusti, Stefania Santopadre, Riccardo Morganti, Francesco Fiorica and 2 more

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In one paragraph

Article in Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Impact of rehabilitation treatment on swallowing during adjuvant radiotherapy following surgery in patients with oral and oropharyngeal cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Stefano UrsinoDepartment of Radiation Oncology, University Hospital S. Chiara, Via Roma 55, Pisa, Italy. stefano.ursino@med.unipi.it.ORCID 0000-0003-3018-2338
Paola CocuzzaDepartment of Radiation Oncology, University Hospital S. Chiara, Via Roma 55, Pisa, Italy.
Veronica SecciaFirst Otorhinolaryngology Unit, University Hospital Cisanello, Via Paradisa 2, Pisa, Italy.
Durim DelishajDepartment of Radiation Oncology, University Hospital S. Chiara, Via Roma 55, Pisa, Italy.
Agostino CristaudoDepartment of Radiation Oncology, University Hospital S. Chiara, Via Roma 55, Pisa, Italy.
Francesco PasqualettiDepartment of Radiation Oncology, University Hospital S. Chiara, Via Roma 55, Pisa, Italy.
Patrizia GiustiDepartment of Radiology, University Hospital Cisanello, Via Paradisa 2, Pisa, Italy.
Stefania SantopadreOtorhinolaryngology-Audiology-Phoniatric Unit, University Hospital Cisanello, Via Paradisa 2, Pisa, Italy.
Riccardo MorgantiDepartment of Clinical and Experimental Medicine, Section of Statistics, Via Roma 55, Pisa, Italy.
Francesco FioricaDepartment of Radiation Oncology, University Hospital Ferrara, Via Aldo Moro 8, Cona, Ferrara, Italy.
Fabiola PaiarDepartment of Radiation Oncology, University Hospital S. Chiara, Via Roma 55, Pisa, Italy.
Bruno FattoriOtorhinolaryngology-Audiology-Phoniatric Unit, University Hospital Cisanello, Via Paradisa 2, Pisa, Italy.
Ospedale Santa Chiara · ITOspedale Cisanello · ITUniversity of Pisa · ITUniversity of Ferrara · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeA prospective instrumental assessment of late dysphagia using swallowing organs at risk (SWOARs)-sparing IMRT for nasopharyngeal and oropharyngeal cancers. MATERIALS AND

methodsObjective instrumental assessment included fiberoptic endoscopic evaluation of swallowing (FEES) and videofluoroscopy (VFS) at baseline, and at 6 and 12 months after treatment. FEES assessed the pharyngeal residue according to the Farneti pooling score (P-score) as follows: 4-5 no dysphagia; 6-7 mild dysphagia; 8-9 moderate dysphagia; 10-11 severe dysphagia. Three different consistencies were tested for the P‑score: liquid (L), semisolid (SS), and solid (S). VFS assessed penetration-aspiration according to the Penetration-Aspiration Scale (PAS) and two different consistencies of the bolus were tested: thin liquid barium (L) and paste barium (S).

results38 patients were evaluable. There was a significant worsening of the P‑score at 6 months both for SS (p = 0.015) and S (p < 0.001), which persisted only for S at 12 months (p < 0.0001). Similarly, there was a significant worsening of the PAS score at 6 and 12 months (p = 0.065 and 0.039, respectively) for the S bolus. Overall, 3-7 and 10-14% aspiration after L and S was observed, respectively.

conclusionsPromising results using a SWOARs-sparing IMRT technique are reported. Therefore, treatment plans should be optimized for reducing doses to these structures.

Indexed as

Deglutition DisordersHead and Neck NeoplasmsRadiotherapy, Intensity-ModulatedDeglutitionHumansNeoplasm Recurrence, LocalProspective StudiesReproducibility of ResultsAspiration-pneumoniaDysphagiaFiberoptic endoscopic evaluation of swallowingRadiotherapyVideofluoroscopy

Identifiers

PMID29987341
OpenAlexW2823759368

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.