Evidence map›Paper›PMID 29987160›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2018

CRACR2A-Mediated TCR Signaling Promotes Local Effector Th1 and Th17 Responses.

Jin Seok Woo, Sonal Srikanth, Kyun-Do Kim, Heidi Elsaesser, Jing Lu, Matteo Pellegrini, David G Brooks, Zuoming Sun, Yousang Gwack

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

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  6. CaJournal of immunology (Baltimore, Md. : 1950) · 2022
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  13. Calcium regulation of T cell metabolismCurrent opinion in physiology · 2020
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Jin Seok WooDepartment of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095.ORCID 0000-0001-8921-2832
Sonal SrikanthDepartment of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095.ORCID 0000-0002-3034-095X
Kyun-Do KimDepartment of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095.ORCID 0000-0001-6872-5583
Heidi ElsaesserPrincess Margaret Cancer Center, University Health Network, Toronto, Ontario M5G 2M9, Canada.
Jing LuDepartment of Molecular, Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA 90095; and.
Matteo PellegriniDepartment of Molecular, Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA 90095; and.
David G BrooksPrincess Margaret Cancer Center, University Health Network, Toronto, Ontario M5G 2M9, Canada.
Zuoming SunDivision of Molecular Immunology, Beckman Research Institute of the City of Hope, Duarte, CA 91010.ORCID 0000-0003-1896-6666
Yousang GwackDepartment of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095; ygwack@mednet.ucla.edu.
University of California, Los Angeles · USUniversity Health Network · CACity of Hope · US

Funding

Women's CancersP30CA016042 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Samuel Wheeler French · 1985 to 2026
$134.5M
Virology CoreP30AI028697 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ANTON, PETER A · 1991 to 2018
$39.9M
UCLA SPORE in Brain CancerP50CA211015 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI David A. Nathanson · 2017 to 2026
$25.2M
Novel regulators of store-operated Ca2+ entry in immune systemsR01AI083432 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GWACK, YOUSANG · 2009 to 2020
$3.8M
Distinct functions of Orai1 and Orai2 in naive and effector helper T cellsR21AI130653 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SRIKANTH, SONAL · 2017 to 2018
$424k
NCI NIH HHS P30 CA016042NCI NIH HHS P50 CA211015NIAID NIH HHS P30 AI028697NIAID NIH HHS R01 AI083432NIAID NIH HHS R21 AI130653
6 · The paper itself

Abstract

Ca

Indexed as

AnimalsArenaviridae InfectionsCalcium-Binding ProteinsCell DifferentiationCells, CulturedCytokinesDisease ResistanceEncephalomyelitis, Autoimmune, ExperimentalHumansLymphocytic choriomeningitis virusMiceMice, KnockoutSignal TransductionTh17 CellsTh1 CellsCalcium-Binding ProteinsCRACR2A protein, humanCracr2a protein, mouseCytokines

Identifiers

PMID29987160
PMCPMC6081249
OpenAlexW2835537973

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.