Evidence map›Paper›PMID 29987105›Full record

ArticleHypertension (Dallas, Tex. : 1979)2018

Objective but Not Subjective Short Sleep Duration Is Associated With Hypertension in Obstructive Sleep Apnea.

Rong Ren, Naima Covassin, Linghui Yang, Yun Li, Ye Zhang, Junying Zhou, Lu Tan, Taomei Li, Xiao Li, Yanyan Wang and 5 more

Abstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Socioeconomic status impacts blood pressure response to positive airway pressure treatment.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022
    Trial
  2. Heart rate and vascular responses to spontaneous arousals following experimental sleep restriction.American journal of physiology. Heart and circulatory physiology · 2026
    Article
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  13. Review
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  15. Article
  16. The Effect of Short Sleep Duration on the Development of Asthma.International journal of clinical practice · 2022
    Review
  17. Review
  18. Article
  19. Effect of Sleep Disturbances on Blood Pressure.Hypertension (Dallas, Tex. : 1979) · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Rong RenFrom the Sleep Medicine Center, Department of Respiratory and Critical Care Medicine, Translational Neuroscience Center, State Key Laboratory, West China Hospital, Sichuan University, Chengdu, China (R.R., L.Y., Y.L., Y.Z., J. Zhou, L.T., T.L., X.L., Y.W., W.L., X.T.).
Naima CovassinDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN (N.C., V.K.S.).
Linghui YangFrom the Sleep Medicine Center, Department of Respiratory and Critical Care Medicine, Translational Neuroscience Center, State Key Laboratory, West China Hospital, Sichuan University, Chengdu, China (R.R., L.Y., Y.L., Y.Z., J. Zhou, L.T., T.L., X.L., Y.W., W.L., X.T.).
Yun LiFrom the Sleep Medicine Center, Department of Respiratory and Critical Care Medicine, Translational Neuroscience Center, State Key Laboratory, West China Hospital, Sichuan University, Chengdu, China (R.R., L.Y., Y.L., Y.Z., J. Zhou, L.T., T.L., X.L., Y.W., W.L., X.T.).
Ye ZhangFrom the Sleep Medicine Center, Department of Respiratory and Critical Care Medicine, Translational Neuroscience Center, State Key Laboratory, West China Hospital, Sichuan University, Chengdu, China (R.R., L.Y., Y.L., Y.Z., J. Zhou, L.T., T.L., X.L., Y.W., W.L., X.T.).
Junying ZhouFrom the Sleep Medicine Center, Department of Respiratory and Critical Care Medicine, Translational Neuroscience Center, State Key Laboratory, West China Hospital, Sichuan University, Chengdu, China (R.R., L.Y., Y.L., Y.Z., J. Zhou, L.T., T.L., X.L., Y.W., W.L., X.T.).
Lu TanFrom the Sleep Medicine Center, Department of Respiratory and Critical Care Medicine, Translational Neuroscience Center, State Key Laboratory, West China Hospital, Sichuan University, Chengdu, China (R.R., L.Y., Y.L., Y.Z., J. Zhou, L.T., T.L., X.L., Y.W., W.L., X.T.).
Taomei LiFrom the Sleep Medicine Center, Department of Respiratory and Critical Care Medicine, Translational Neuroscience Center, State Key Laboratory, West China Hospital, Sichuan University, Chengdu, China (R.R., L.Y., Y.L., Y.Z., J. Zhou, L.T., T.L., X.L., Y.W., W.L., X.T.).
Xiao LiFrom the Sleep Medicine Center, Department of Respiratory and Critical Care Medicine, Translational Neuroscience Center, State Key Laboratory, West China Hospital, Sichuan University, Chengdu, China (R.R., L.Y., Y.L., Y.Z., J. Zhou, L.T., T.L., X.L., Y.W., W.L., X.T.).
Yanyan WangFrom the Sleep Medicine Center, Department of Respiratory and Critical Care Medicine, Translational Neuroscience Center, State Key Laboratory, West China Hospital, Sichuan University, Chengdu, China (R.R., L.Y., Y.L., Y.Z., J. Zhou, L.T., T.L., X.L., Y.W., W.L., X.T.).
Jihui ZhangDepartment of Psychiatry, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong SAR (J. Zhang, Y.-K.W.).
Yun-Kwok WingDepartment of Psychiatry, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong SAR (J. Zhang, Y.-K.W.).
Weimin LiFrom the Sleep Medicine Center, Department of Respiratory and Critical Care Medicine, Translational Neuroscience Center, State Key Laboratory, West China Hospital, Sichuan University, Chengdu, China (R.R., L.Y., Y.L., Y.Z., J. Zhou, L.T., T.L., X.L., Y.W., W.L., X.T.).
Virend K SomersDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN (N.C., V.K.S.).
Xiangdong TangFrom the Sleep Medicine Center, Department of Respiratory and Critical Care Medicine, Translational Neuroscience Center, State Key Laboratory, West China Hospital, Sichuan University, Chengdu, China (R.R., L.Y., Y.L., Y.Z., J. Zhou, L.T., T.L., X.L., Y.W., W.L., X.T.).

Funding

Disease Mechanisms in Sleep ApneaR01HL065176 · NHLBI · MAYO CLINIC ROCHESTER · PI SOMERS, VIREND K · 1999 to 2021
$5.8M
Sleep Enhancement to Decrease Blood Pressure: A Randomized, Controlled TrialR01HL134808 · NHLBI · MAYO CLINIC ROCHESTER · PI SOMERS, VIREND K · 2017 to 2021
$3.9M
Sleep Restriction and Augmented Vascular Risk in PrehypertensionR01HL114676 · NHLBI · MAYO CLINIC ROCHESTER · PI SOMERS, VIREND K · 2012 to 2016
$2.4M
NHLBI NIH HHS R01 HL065176NHLBI NIH HHS R01 HL114676NHLBI NIH HHS R01 HL134808
6 · The paper itself

Abstract

Extremes of sleep duration and obstructive sleep apnea (OSA) are both associated with hypertension. We aimed to explore whether sleep duration modifies the relationship between OSA and prevalent hypertension, using both objective and subjective measures of total sleep duration. A total of 7107 OSA patients and 1118 primary snorers were included in the study. Hypertension was defined based either on direct blood pressure measures or on diagnosis by a physician. Objective sleep duration was derived by polysomnography and subjective sleep duration was self-reported. Logistic regression models were used to estimate the associations between objective/subjective sleep duration and hypertension prevalence in OSA and primary snorers. Compared with primary snorers, OSA combined with objective sleep duration of 5 to 6 hours increased the odds of hypertension by 45% (odds ratio, 1.45; 95% confidence interval, 1.14-1.84), whereas OSA combined with objective sleep duration <5 hours further increased the odds of hypertension by 80% (odds ratio, 1.80; 95% confidence interval, 1.33-2.42). These results were independent of major confounding factors frequently associated with OSA or hypertension. In stratified analysis by sleep duration, risk of hypertension in those with extremely short sleep (<5 hours) was not significantly different between OSA and primary snorers, whereas odds were significant for OSA in the other 4 sleep duration strata (5-6, 6-7, 7-8, and >8 hours). No significance was evident using subjective sleep duration. We conclude that objective short sleep duration is associated with hypertension in OSA patients. Extremely short sleep duration in itself may actually be even more detrimental than OSA in terms of hypertension risk.

Indexed as

AdultBlood PressureCross-Sectional StudiesFemaleHumansHypertensionLogistic ModelsMaleMiddle AgedPolysomnographyRisk FactorsSleepSleep Apnea, ObstructiveSnoringTime Factorsblood pressurehypertensionpolysomnographysleepsleep apnea, obstructive

Identifiers

PMID29987105
PMCPMC6512952

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.