Trial reportProceedings of the National Academy of Sciences of the United States of America2018
Enhanced brain activity associated with memory access in highly superior autobiographical memory.
Trial report in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 59 citations in OpenAlex.
- A Systematic Review and Meta-analysis of the Neural Correlates of Direct vs. Generative Retrieval of Episodic Autobiographical Memory.Neuropsychology review · 2025Pooled it
- Highly Superior Autobiographical Memory (HSAM): A Systematic Review.Neuropsychology review · 2025Pooled it
- Common and distinct correlates of construction and elaboration of episodic-autobiographical memory: An ALE meta-analysis.Cortex; a journal devoted to the study of the nervous system and behavior · 2023Pooled it
- Remoteness sensitive theta network dynamics during early autobiographical memory access.Scientific reports · 2026Article
- Article
- Recalling more each time: context change effects in hypermnesia.Cognitive processing · 2025Article
- Unveiling the neural network involved in mentally projecting the self through episodic autobiographical memories.Scientific reports · 2025Article
- Exploring Inhibitory Control Processes in Highly Superior Autobiographical Memory (HSAM): A Single Case Study.Journal of cognition · 2025Article
- Article
- Common neural substrates of diverse neurodevelopmental disorders.Brain : a journal of neurology · 2023Article
- Cognitive and neural mechanisms underlying false memories: misinformation, distortion or erroneous configuration?AIMS neuroscience · 2023Review
- Sex-Related Differences in Voluntary Alcohol Intake and mRNA Coding for Synucleins in the Brain of Adult Rats Prenatally Exposed to Alcohol.Biomedicines · 2022Article
- Neuropsychological implication in possible antibody-negative limbic encephalitis: a clinical case report.The Journal of international medical research · 2022Article
- The seven sins of memory: an update.Memory (Hove, England) · 2022Review
- No Association Between Loneliness, Episodic Memory and Hippocampal Volume Change in Young and Healthy Older Adults: A Longitudinal European Multicenter Study.Frontiers in aging neuroscience · 2022Article
- Early life stress is associated with the default mode and fronto-limbic network connectivity among young adults.Frontiers in behavioral neuroscience · 2022Article
- Destination memory: Memory associated with social interactions.Frontiers in psychology · 2022Review
- fMRI evidence reveals emotional biases in bilingual decision making.Brain structure & function · 2021Article
- Differentiating Real-World Autobiographical Experiences without Recourse to Behaviour.Brain sciences · 2021Article
- Multiple Exposures Enhance Both Item Memory and Contextual Memory Over Time.Frontiers in psychology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Brain systems underlying human memory function have been classically investigated studying patients with selective memory impairments. The discovery of rare individuals who have highly superior autobiographical memory (HSAM) provides, instead, an opportunity to investigate the brain systems underlying enhanced memory. Here, we carried out an fMRI investigation of a group of subjects identified as having HSAM. During fMRI scanning, eight subjects with HSAM and 21 control subjects were asked to retrieve autobiographical memories (AMs) as well as non-AMs (e.g., examples of animals). Subjects were instructed to signal the "access" to an AM by a key press and to continue "reliving" it immediately after. Compared with controls, individuals with HSAM provided a richer AM recollection and were faster in accessing AMs. The access to AMs was associated with enhanced prefrontal/hippocampal functional connectivity. AM access also induced increased activity in the left temporoparietal junction and enhanced functional coupling with sensory cortices in subjects with HSAM compared with controls. In contrast, subjects with HSAM did not differ from controls in functional activity during the reliving phase. These findings, based on fMRI assessment, provide evidence of interaction of brain systems engaged in memory retrieval and suggest that enhanced activity of these systems is selectively involved in enabling more efficient access to past experiences in HSAM.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.