Evidence map›Paper›PMID 29986894›Full record

ArticleInfection and immunity2018

Tailoring a Plasmodium vivax Vaccine To Enhance Efficacy through a Combination of a CSP Virus-Like Particle and TRAP Viral Vectors.

Erwan Atcheson, Karolis Bauza, Ahmed M Salman, Eduardo Alves, Joshua Blight, Martha Eva Viveros-Sandoval, Chris J Janse, Shahid M Khan, Adrian V S Hill, Arturo Reyes-Sandoval

Open access · hybridAbstract read
In one paragraph

Article in Infection and immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 35 citations in OpenAlex.

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  14. Monoclonal antibodies for malaria prevention.Molecular therapy : the journal of the American Society of Gene Therapy · 2022
    Review
  15. Frontiers in cellular and infection microbiology · 2022
    Review
  16. Frontiers in immunology · 2022
    Review
  17. Article
  18. Article
  19. Progress towards the development of aExpert review of vaccines · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Erwan AtchesonThe Jenner Institute, University of Oxford, Oxford, United Kingdom.
Karolis BauzaThe Jenner Institute, University of Oxford, Oxford, United Kingdom.
Ahmed M SalmanThe Jenner Institute, University of Oxford, Oxford, United Kingdom.
Eduardo AlvesThe Jenner Institute, University of Oxford, Oxford, United Kingdom.
Joshua BlightThe Jenner Institute, University of Oxford, Oxford, United Kingdom.
Martha Eva Viveros-SandovalLaboratorio de Hemostasia y Biología Vascular, División de Estudios de Posgrado, Facultad de Ciencias Médicas y Biológicas Dr. Ignacio Chávez, Universidad Michoacana de San Nicolás de Hidalgo (UMSNH), Morelia, Michoacán, Mexico.
Chris J JanseLeiden Malaria Research Group, Department of Parasitology, Center of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands.
Shahid M KhanLeiden Malaria Research Group, Department of Parasitology, Center of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands.
Adrian V S HillThe Jenner Institute, University of Oxford, Oxford, United Kingdom.
Arturo Reyes-SandovalThe Jenner Institute, University of Oxford, Oxford, United Kingdom arturo.reyes@ndm.ox.ac.uk.ORCID https://orcid.org/0000-0002-2648-1696
University of Oxford · GBLeiden University Medical Center · NLUniversidad Michoacana de San Nicolás de Hidalgo · MX

Funding

Medical Research Council MR/N019008/1Wellcome TrustWellcome Trust 095540/Z/11/ZWellcome Trust 097395/Z/11/Z
6 · The paper itself

Abstract

Vivax malaria remains one of the most serious and neglected tropical diseases, with 132 to 391 million clinical cases per year and 2.5 billion people at risk of infection. A vaccine against

Indexed as

AdenoviridaeAdjuvants, ImmunologicAnimalsAntibodies, ProtozoanAntigens, ProtozoanFemaleGenetic VectorsMalaria VaccinesMalaria, VivaxMiceMice, Inbred BALB CNanoparticlesPlasmodium bergheiPlasmodium vivaxPolysorbatesProtozoan ProteinsAddavaxAdjuvants, ImmunologicAntibodies, ProtozoanAntigens, Protozoancircumsporozoite protein, ProtozoanMalaria VaccinesMatrix-MPolysorbatesProtozoan ProteinsSaponinsSqualenethrombospondin-related adhesive protein, protozoanVaccines, Virus-Like ParticleadenovirusesmalariaPlasmodium vivaxvaccinesVLP

Identifiers

PMID29986894
PMCPMC6105880
OpenAlexW2868592073

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.