Evidence map›Paper›PMID 29986855›Full record

ArticleBlood advances2018

Human adult HSCs can be discriminated from lineage-committed HPCs by the expression of endomucin.

Kristian Reckzeh, Hüsün Kizilkaya, Alexandra Søgaard Helbo, Montserrat Estruch Alrich, André Gundersen Deslauriers, Amit Grover, Nicolas Rapin, Fazila Asmar, Kirsten Grønbæk, Bo Porse and 4 more

Abstract read
In one paragraph

Article in Blood advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Research progress on the structure and function of endomucin.Animal models and experimental medicine · 2020
    Review
  7. Article
  8. Hematopoietic Stem Cell Heterogeneity.Advances in experimental medicine and biology · 2019
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Kristian ReckzehFinsen Laboratory, Rigshospitalet, Faculty of Health and Medical Sciences.ORCID 0000-0001-6391-625X
Hüsün KizilkayaFinsen Laboratory, Rigshospitalet, Faculty of Health and Medical Sciences.
Alexandra Søgaard HelboFinsen Laboratory, Rigshospitalet, Faculty of Health and Medical Sciences.
Montserrat Estruch AlrichFinsen Laboratory, Rigshospitalet, Faculty of Health and Medical Sciences.ORCID 0000-0002-7162-4158
André Gundersen DeslauriersFinsen Laboratory, Rigshospitalet, Faculty of Health and Medical Sciences.
Amit GroverMRC Molecular Hematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom.
Nicolas RapinFinsen Laboratory, Rigshospitalet, Faculty of Health and Medical Sciences.ORCID 0000-0001-5208-8874
Fazila AsmarDepartment of Hematology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; and.
Kirsten GrønbækBiotech Research and Innovation Center, Faculty of Health and Medical Sciences.ORCID 0000-0002-1535-9601
Bo PorseFinsen Laboratory, Rigshospitalet, Faculty of Health and Medical Sciences.ORCID 0000-0001-6043-0844
Niels BorregaardDepartment of Hematology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; and.
Dietmar VestweberMax Planck Institute for Molecular Biomedicine, University of Münster, Münster, Germany.ORCID 0000-0002-3517-732X
Claus NerlovMRC Molecular Hematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom.ORCID 0000-0002-0544-735X
Kim Theilgaard-MönchFinsen Laboratory, Rigshospitalet, Faculty of Health and Medical Sciences.ORCID 0000-0002-4239-4939

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Medical Research Council G0900892Medical Research Council MC_UU_00016/7Medical Research Council MC_UU_12009/7NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene Expression RegulationAdultAdult Stem CellsHematopoietic Stem CellsHumansSialoglycoproteinsEMCN protein, humanSialoglycoproteins

Identifiers

PMID29986855
PMCPMC6039657

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.