ReviewAnnals of clinical microbiology and antimicrobials2018
Streptococcus pyogenes-purpura fulminans as an invasive form of group A streptococcal infection.
Review in Annals of clinical microbiology and antimicrobials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 27 citations in OpenAlex.
- Fulminant streptococcal toxic shock syndrome presenting as cervical epidural abscess: a case report.Journal of Yeungnam medical science · 2026Article
- Group A β-hemolytic streptococcus causing purpura fulminans: two case reports.Frontiers in immunology · 2026Article
- Experimental and In Silico Studies to Unravel the Antioxidant and Antibacterial Properties of Lichen Metabolites fromAntioxidants (Basel, Switzerland) · 2025Article
- Acute Infectious Purpura Fulminans Complicated by Bacterial Translocation after Rectal Cancer Surgery: A Case Report.Medicina (Kaunas, Lithuania) · 2024Article
- Recombinant human soluble thrombomodulin and danaparoid combination anticoagulant therapy for disseminated intravascular coagulation in a child with streptococcal toxic shock syndrome: A case report.Experimental and therapeutic medicine · 2022Article
- Hypofibrinogenemia is associated with a high degree of risk in infectious diseases: a post-hoc analysis of post-marketing surveillance of patients with disseminated intravascular coagulation treated with thrombomodulin alfa.Thrombosis journal · 2021Article
- A Review ofPathogens (Basel, Switzerland) · 2021Review
- Clinical and Histopathologic Characteristics of the Main Causes of Vascular Occlusion - Part I: Thrombi.Actas dermo-sifiliograficas · 2021Review
- Septic Shock and Purpura Fulminans Due to Streptococcus pneumoniae Bacteremia in an Unvaccinated Immunocompetent Adult: Case Report and Review.The American journal of case reports · 2020Review
- [Acute fever with rash, necrosis, and bullae in both lower extremities in a 12-year-old girl].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2020Article
- Vasculitis with nonpalpable purpura resembling purpura fulminans.Clinical and experimental nephrology · 2020Article
- Acute infectious purpura fulminans withIDCases · 2019Article
Corrections and comments
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Authors and funding
14 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundStreptococcus pyogenes is an uncommon pathogen of purpura fulminans, and the pathogenesis of S. pyogenes-purpura fulminans remains unclear because of paucity of cases. We reported a pediatric case of S. pyogenes-purpura fulminans with literature review of the disease. CASE PRESENTATION: A 3-year-old boy showed limping, lethargy and acral gangrene within 24 h. A diagnosis of S. pyogenes-purpura fulminans was made for bacterial isolation from throat and peripheral blood. Intensive therapy led to a survival with amputation of the left distal metatarsal bone, and normal development. The isolated M12 carried no mutation of csrS/R or rgg. Thrombophilia or immunodeficiency was excluded. DISCUSSION: Twelve-reported cases (9 pediatric and 3 elderly) of S. pyogenes-purpura fulminans started with shock and coagulopathy. Five patients age < 8 years had no underlying disease and survived. One youngest and two immunocompromised patients died.
conclusionStreptococcus pyogenes-acute infectious purpura fulminans is a distinctive rare form of aggressive GAS infections.
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