ArticleHealth and quality of life outcomes2018
Prospective evaluation of the Quality of Life after Brain Injury (QOLIBRI) score: minor differences in patients with major versus no or mild traumatic brain injury at one-year follow up.
Article in Health and quality of life outcomes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02165137 (Quality Control in the Management of Major Trauma Patients at Aarau Cantonal Hospital - Evaluation of Processes and Patient Outcome), which is not on this map. Cited by 22 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Quality Control in the Management of Major Trauma Patients at Aarau Cantonal Hospital - Evaluation of Processes and Patient Outcome
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Parameters influencing health-related quality of life after severe trauma: a systematic review (part II).European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024Pooled it
- Health-related quality of life after severe trauma and available PROMS: an updated review (part I).European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023Pooled it
- Tranexamic acid to reduce head injury death in people with traumatic brain injury: the CRASH-3 international RCT.Health technology assessment (Winchester, England) · 2021Trial
- Cost-effectiveness analysis of tranexamic acid for the treatment of traumatic brain injury, based on the results of the CRASH-3 randomised trial: a decision modelling approach.BMJ global health · 2020Trial
- Systematic review of health utility losses from injuries and violence.Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention · 2026Article
- One-Year Outcomes After Traumatic Brain Injury and Early Extracranial Surgery in the TRACK-TBI Study.JAMA network open · 2025Observational
- The relationship between social participation and quality of life in individuals with traumatic brain injury.Fujita medical journal · 2025Article
- Optimal Timing of Exercise for Enhanced Learning and Memory: Insights From CA1 and CA3 Regions in Traumatic Brain Injury Model in Male Rats.Brain and behavior · 2025Article
- Health-related quality of life among inpatients suffering from Traumatic brain injury in an urban setting in Vietnam.PloS one · 2024Article
- Traumatic Brain Injury in Cameroon: A Prospective Observational Study in a Level I Trauma Centre.Medicina (Kaunas, Lithuania) · 2023Observational
- Longitudinal Internal Validity of the Quality of Life after Brain Injury: Response Shift and Responsiveness.Journal of clinical medicine · 2023Article
- Functional Recovery, Symptoms, and Quality of Life 1 to 5 Years After Traumatic Brain Injury.JAMA network open · 2023Article
- Long-term health-related quality of life after trauma with and without traumatic brain injury: a prospective cohort study.Scientific reports · 2023Article
- Sensitivity of outcome instruments in a priori selected patient groups after traumatic brain injury: Results from the CENTER-TBI study.PloS one · 2023Article
- Health-related quality of life and return to work 1 year after major trauma from a network perspective.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022Article
- Granulocyte colony-stimulating factor protected against brain injury in a rat cerebral hemorrhage model by modulating inflammation.Experimental animals · 2022Article
- Article
- Determinants of long-term health-related quality of life in adult patients with mild traumatic brain injury.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2021Article
- Predicting the Health-related Quality of Life in Patients Following Traumatic Brain Injury.Surgery journal (New York, N.Y.) · 2021Article
- Comparison of Four Quality of Life Inventories for Patients with Traumatic Brain Injuries and Orthopedic Injuries.Journal of neurotrauma · 2020Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe Quality of Life after Brain Injury (QOLIBRI) score was developed to assess disease-specific health-related quality of life (HRQoL) after traumatic brain injury (TBI). So far, validation studies on the QOLIBRI were only conducted in cohorts with traumatic brain injury. This study investigated the longer-term residuals in severely injured patients, focusing specifically on the possible impact of major TBI.
methodsIn a prospective questionnaire investigation, 199 survivors with an injury severity score (ISS) > 15 participated in one-year follow-up. Patients who had sustained major TBI (abbreviated injury scale, AIS head > 2) were compared with patients who had no or only mild TBI (AIS head ≤ 2). Univariate analysis (ANOVA, Cohen's kappa, Pearson's r) and stepwise linear regression analysis (B with 95% CI, R, R
resultsThe total QOLIBRI revealed no differences in one-year outcomes between patients with versus without major TBI (75 and 76, resp.; p = 0.68). With regard to the cognitive subscore, the group with major TBI demonstrated significantly more limitations than the one with no or mild TBI (p < 0.05). The AIS head correlated significantly with the cognitive dimension of the QOLIBRI (r = - 0.16; p < 0.05), but not with the mental components of the SF-36 or the TOP. In multivariate analysis, the influence of the severity of head injury (AIS head) on total QOLIBRI was weaker than that of injured extremities (R
conclusionsGiven the unexpected result of similar mean QOLIBRI total score values and only minor differences in cognitive deficits following major trauma independently of whether patients sustained major brain injury or not, further studies should investigate whether the QOLIBRI actually has the discriminative capacity to detect specific residuals of major TBI. In effect, the score appears to indicate mental deficits following different types of severe trauma, which should be evaluated in more detail.
trial registrationNCT02165137 ; retrospectively registered 11 June 2014.
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