Evidence map›Paper›PMID 29986658›Full record

ArticleBMC infectious diseases2018

Prevalence and associated knowledge of hepatitis B infection among healthcare workers in Freetown, Sierra Leone.

Yu-Ling Qin, Bo Li, Yue-Su Zhou, Xin Zhang, Lei Li, Bing Song, Peng Liu, Yue Yuan, Zhong-Peng Zhao, Jun Jiao and 9 more

Abstract read
In one paragraph

Article in BMC infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Knowledge, attitudes and practices to hepatitis B among South African primary healthcare staff.African journal of primary health care & family medicine · 2025
    Article
  7. Article
  8. Hepatitis B immunisation and immune status of nurses in a regional hospital in central South Africa.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2024
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  20. Prevalence of viral hepatitis B and C in Sierra Leone-current knowledge and knowledge gaps: a narrative review.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Yu-Ling QinBeijing 302 Hospital, Beijing, China.
Bo LiBeijing 302 Hospital, Beijing, China.
Yue-Su ZhouBeijing 302 Hospital, Beijing, China.
Xin ZhangBeijing 302 Hospital, Beijing, China.
Lei LiBeijing 302 Hospital, Beijing, China.
Bing SongBeijing 302 Hospital, Beijing, China.
Peng LiuBeijing 302 Hospital, Beijing, China.
Yue YuanBeijing 302 Hospital, Beijing, China.
Zhong-Peng ZhaoBeijing Institute of Microbiology and Epidemiology, Beijing, China.
Jun JiaoBeijing Institute of Microbiology and Epidemiology, Beijing, China.
Jing LiBeijing Institute of Microbiology and Epidemiology, Beijing, China.
Yi SunBeijing Institute of Microbiology and Epidemiology, Beijing, China.
Stephen SevalieNo. 34 Military Hospital, Wilberforce, Freetown, Sierra Leone.
Joseph E KanuNo. 34 Military Hospital, Wilberforce, Freetown, Sierra Leone.
Ya-Jun SongBeijing Institute of Microbiology and Epidemiology, Beijing, China.
Jia-Fu JiangBeijing Institute of Microbiology and Epidemiology, Beijing, China. jiangjf2008@gmail.com.ORCID 0000-0003-2624-7450
Foday SahrNo. 34 Military Hospital, Wilberforce, Freetown, Sierra Leone. fodaysahr1@gmail.com.
Tian-Jun JiangBeijing 302 Hospital, Beijing, China. aba302@163.com.
Chinese Military Medical Experts Group in Sierra Leone

Funding

a training grant by Beijing 302 Hospital, China YNKT20170080
6 · The paper itself

Abstract

backgroundHepatitis B virus (HBV) is considered highly prevalent in West Africa. However, major gaps in surveillance exist in Sierra Leone. Although healthcare workers (HCWs) are at high risk for HBV infection, little is known about the prevalence and knowledge of hepatitis B among HCWs in Sierra Leone.

methodsA cross-sectional study of all HCWs at the No. 34 Military Hospital located in Freetown, Sierra Leone, was conducted from March 20 to April 10, 2017. Whole blood was collected and screened for HBV markers using a one-step rapid immunochromatographic test with positive samples tested for HBV DNA. Additionally, questionnaires assessing self-reported knowledge of HBV infections were administered to all participants. Data were processed and analyzed using SPSS (version 17.0) software.

resultsA total of 211 HCWs were included in this study with a median age of 39.0 years (range: 18-59). Of the participating HCWs, 172 (81.5%) participants were susceptible (all markers negative), 21(10.0%) were current HBV (HBsAg positive) and nine (4.3%) were considered immune because of past infection (HBsAg negative and anti-HBc positive; anti-HBs positive). Additionally, nine (4.3%) participants displayed immunity to the virus as a result of prior hepatitis B vaccination (only anti-HBs positive). Of the 21 HCWs with positive HBsAg, 13 (61.9%) had detectable HBV DNA. There was a significantly lower risk for current HBV infection among HCWs older than 39 years (OR 0.337, p = 0.046). In addition, only 14 (6.6%), 73 (34.6%) and 82 (38.9%) participants in this survey had adequate knowledge about the clinical outcome, routes of transmission, and correct preventive measures of HBV infection, respectively.

conclusionsHCWs in Sierra Leone lacked adequate knowledge of the hepatitis B virus. Additionally, the low coverage rate of hepatitis B vaccination among HCWs fails to meet WHO recommendations, leaving many of the sampled HCWs susceptible to infection. This study reaffirms the need for more intensive training for HCWs in addition to strengthening vaccination programmes to protect HCWs against HBV in Sierra Leone.

Indexed as

Health Knowledge, Attitudes, PracticeAdolescentAdultCross-Sectional StudiesFemaleHealth PersonnelHepatitis BHepatitis B Surface AntigensHepatitis B VaccinesHepatitis B virusHumansMaleMiddle AgedPrevalenceSierra LeoneSurveys and QuestionnairesHepatitis B Surface AntigensHepatitis B VaccinesHealthcare workersHepatitis B virusPrevalenceSierra Leone

Identifiers

PMID29986658
PMCPMC6038231

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.