Evidence map›Paper›PMID 29986533›Full record

ArticleInternational journal of molecular sciences2018

In Vitro Model of Neuroinflammation: Efficacy of Cannabigerol, a Non-Psychoactive Cannabinoid.

Agnese Gugliandolo, Federica Pollastro, Gianpaolo Grassi, Placido Bramanti, Emanuela Mazzon

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 2 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 2 syntheses or guidelines pooled it, 102 citations in OpenAlex.

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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Agnese GugliandoloIRCCS Centro Neurolesi "Bonino Pulejo", 98124 Messina, Italy. agnesegugli@hotmail.it.
Federica PollastroDepartment of Pharmaceutical Sciences, University of Eastern Piedmont "Amedeo Avogadro", 28100 Novara, Italy. federica.pollastro@uniupo.it.ORCID 0000-0002-0949-2799
Gianpaolo GrassiResearch Centre for Industrial Crops, Council for Agricultural Research and Economics (CREA-CIN), 45100 Rovigo, Italy. giampaolo.grassi@gmail.com.
Placido BramantiIRCCS Centro Neurolesi "Bonino Pulejo", 98124 Messina, Italy. placido.bramanti@irccsme.it.
Emanuela MazzonIRCCS Centro Neurolesi "Bonino Pulejo", 98124 Messina, Italy. emazzon.irccs@gmail.com.ORCID 0000-0002-5073-717X
Centro Neurolesi Bonino Pulejo · ITResearch Centre for Cereal and Industrial Crops · ITUniversità degli Studi del Piemonte Orientale “Amedeo Avogadro” · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation and oxidative stress play main roles in neurodegeneration. Interestingly, different natural compounds may be able to exert neuroprotective actions against inflammation and oxidative stress, protecting from neuronal cell loss. Among these natural sources,

Indexed as

AnimalsAnti-Inflammatory AgentsApoptosisbcl-2-Associated X ProteinCannabinoidsCaspase 3Cells, CulturedCulture MediaGene Expression RegulationLipopolysaccharidesMacrophagesMiceMotor NeuronsNeuroprotective AgentsOxidative StressProto-Oncogene Proteins c-bcl-2Anti-Inflammatory AgentsBax protein, mousebcl-2-Associated X ProteincannabigerolCannabinoidsCasp3 protein, mouseCaspase 3Culture MediaLipopolysaccharidesNeuroprotective AgentsProto-Oncogene Proteins c-bcl-2cannabigerolCannabis sativaneuroinflammationoxidative stressphytocannabinoid

Identifiers

PMID29986533
PMCPMC6073490
OpenAlexW2839224853

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.