Evidence map›Paper›PMID 29986480›Full record

ArticleDiseases (Basel, Switzerland)2018

Grape Pomace: Antioxidant Activity, Potential Effect Against Hypertension and Metabolites Characterization after Intake.

Zuriñe Rasines-Perea, Isabelle Ky, Gérard Cros, Alan Crozier, Pierre-Louis Teissedre

Open access · goldAbstract read
In one paragraph

Article in Diseases (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Natural Products to Promote Vascular Health.Handbook of experimental pharmacology · 2025
    Review
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  6. Article
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  13. Article
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  15. Article
  16. Article
  17. Article
  18. Review
  19. Special Issue: Wine and Vine Components and Health.Diseases (Basel, Switzerland) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Zuriñe Rasines-PereaUniv Bordeaux, Unité de recherche Œnologie, EA 4577, USC 1366 INRA, ISVV, 33882 Villenave d'Ornon CEDEX, France. zrasines@hotmail.es.
Isabelle KyUniv Bordeaux, Unité de recherche Œnologie, EA 4577, USC 1366 INRA, ISVV, 33882 Villenave d'Ornon CEDEX, France. isabelleky@gmail.com.
Gérard CrosInstitut des Biomolécules Max Mousseron (IBMM), UMR CNRS-5247, Universités Montpellier 1 et 2, Ecole Nationale Supérieure de Chimie de Montpellier, BP 14491, 34093 Montpellier CEDEX 5, France. gerard.cros@umontpellier.fr.
Alan CrozierDepartment of Nutrition, University of California, Davis, CA 95616, USA. alan.crozier44@gmail.com.
Pierre-Louis TeissedreUniv Bordeaux, Unité de recherche Œnologie, EA 4577, USC 1366 INRA, ISVV, 33882 Villenave d'Ornon CEDEX, France. pierre-louis.teissedre@u-bordeaux.fr.ORCID 0000-0002-0115-5456
Université de Bordeaux · FRÉcole Nationale Supérieure de Chimie de Montpellier · FRUniversity of California, Davis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Observational studies indicate that the intake of polyphenol-rich foods improves vascular health, thereby significantly reducing the risk of hypertension and cardiovascular disease (CVD). Therefore, the aim of this study was to analyse the remained potential of grape by-products from important Rhône Valley red wine cultivars: Grenache, Syrah, Carignan, Mourvèdre and Alicante. For that, six different extracts from grape pomaces, selected by their antioxidant activity, were studied in vivo during six weeks with spontaneously hypertensive rats (SHR). Extracts used in SHR1, SHR2 and SHR6 groups presented a « rebound effect » on systolic blood pressure, whereas the other extracts do not change it significantly. The bioavailability of Grenache (GRE1) (EA70) seed pomace extract (SHR1 group), Mouvendre (MOU) (EA70) skin pomace extract (SHR5 group) and Alicante (ALI) (EA70) skin pomace extract (SHR6 group) was studied by High Performance Liquid Chromatography with Photodiode Array detector and Electrospray Ionization Mass Spectrometer (HPLC-PDA-ESI-MS

Indexed as

grape pomacehypertensionmetabolites characterizationpolyphenols

Identifiers

PMID29986480
PMCPMC6163875
OpenAlexW2826589182

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.