Evidence map›Paper›PMID 29986160›Full record

ReviewAnnual review of neuroscience2018

Computational Principles of Supervised Learning in the Cerebellum.

Jennifer L Raymond, Javier F Medina

Abstract readReview
In one paragraph

Review in Annual review of neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 129 papers.

0numbers the graph read from it
0cells of the map it votes in
129citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

129 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Unsupervised nonmotor learning in the human cerebellum.bioRxiv : the preprint server for biology · 2026
    Article
  5. The Human Cerebellum Encodes Temporally Sensitive Reinforcement Learning Signals.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  6. Critical period plasticity enables credit assignment.bioRxiv : the preprint server for biology · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Consensus Paper: Models of Cerebellar Functions.Cerebellum (London, England) · 2026
    Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

69 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jennifer L RaymondDepartment of Neurobiology, Stanford University School of Medicine, Stanford, California 94305, USA; email: jennifer.raymond@stanford.edu.
Javier F MedinaDepartment of Neuroscience, Baylor College of Medicine, Houston, Texas 77030, USA; email: jfmedina@bcm.edu.

Funding

Coding and processing of error signals in inferior olivary-cerebellar networksR01MH093727 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI JAVIER F MEDINA · 2011 to 2026
$6.7M
The impact of cerebellar tDCS in local and downstream brain circuits: how much is neuralactivity modulated in the resting state and during sensorimotor processing?RF1MH114269 · NIMH · BAYLOR COLLEGE OF MEDICINE · PI MEDINA, JAVIER F · 2017 to 2017
$2.0M
Targets of low dose alcohol during cerebellar-driven behavior in miceR21AA025572 · NIAAA · BAYLOR COLLEGE OF MEDICINE · PI MEDINA, JAVIER F · 2016 to 2017
$445k
NIAAA NIH HHS R21 AA025572NIMH NIH HHS R01 MH093727NIMH NIH HHS RF1 MH114269
6 · The paper itself

Abstract

Supervised learning plays a key role in the operation of many biological and artificial neural networks. Analysis of the computations underlying supervised learning is facilitated by the relatively simple and uniform architecture of the cerebellum, a brain area that supports numerous motor, sensory, and cognitive functions. We highlight recent discoveries indicating that the cerebellum implements supervised learning using the following organizational principles: ( a) extensive preprocessing of input representations (i.e., feature engineering), ( b) massively recurrent circuit architecture, ( c) linear input-output computations, ( d) sophisticated instructive signals that can be regulated and are predictive, ( e) adaptive mechanisms of plasticity with multiple timescales, and ( f) task-specific hardware specializations. The principles emerging from studies of the cerebellum have striking parallels with those in other brain areas and in artificial neural networks, as well as some notable differences, which can inform future research on supervised learning and inspire next-generation machine-based algorithms.

Indexed as

Models, NeurologicalSupervised Machine LearningAlgorithmsAnimalsCerebellumHumansNerve NetNeuronal PlasticityNeuronsTime Factorsclimbing fiberconsolidationdecorrelationmachine learningplasticityPurkinje cell

Identifiers

PMID29986160
PMCPMC6056176

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.