Evidence map›Paper›PMID 29986054›Full record

ArticleNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association2019

Acute kidney injury following coronary revascularization procedures in patients with advanced CKD.

Abduzhappar Gaipov, Miklos Z Molnar, Praveen K Potukuchi, Keiichi Sumida, Zoltan Szabo, Oguz Akbilgic, Elani Streja, Connie M Rhee, Santhosh K G Koshy, Robert B Canada and 2 more

Open access · bronzeAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Acute Kidney Injury after Isolated Coronary Bypass Surgery.The International journal of angiology : official publication of the International College of Angiology, Inc · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 5 countries.

Abduzhappar GaipovDivision of Nephrology, Department of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
Miklos Z MolnarDivision of Transplant Surgery, Methodist University Hospital Transplant Institute, Memphis, TN, USA.
Praveen K PotukuchiDivision of Nephrology, Department of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
Keiichi SumidaDivision of Nephrology, Department of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
Zoltan SzaboDepartment of Cardiothoracic Surgery and Anesthesia, Linköping University Hospital, Linköping, Sweden.
Oguz AkbilgicCenter for Biomedical Informatics, Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, USA.
Elani StrejaHarold Simmons Center for Chronic Disease Research and Epidemiology, Division of Nephrology and Hypertension, University of California, Irvine, Orange, CA, USA.
Connie M RheeHarold Simmons Center for Chronic Disease Research and Epidemiology, Division of Nephrology and Hypertension, University of California, Irvine, Orange, CA, USA.
Santhosh K G KoshyDivision of Cardiology, Department of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
Robert B CanadaDivision of Nephrology, Department of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
Kamyar Kalantar-ZadehHarold Simmons Center for Chronic Disease Research and Epidemiology, Division of Nephrology and Hypertension, University of California, Irvine, Orange, CA, USA.
Csaba P KovesdyDivision of Nephrology, Department of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
University of Tennessee Health Science Center · USUniversity of California, Irvine · USLinköping University · SESemmelweis University · HU

Funding

Transition of Care in CKD (TC-CKD)U01DK102163 · NIDDK · UNIVERSITY OF CALIFORNIA-IRVINE · PI JACOBSEN, STEVEN J, KALANTAR-ZADEH, KAMYAR · 2014 to 2018
$2.8M
MALNUTRITION, DIET AND RACIAL DISPARITIES IN CKDK24DK091419 · NIDDK · UNIVERSITY OF CALIFORNIA-IRVINE · PI KALANTAR-ZADEH, KAMYAR · 2011 to 2020
$1.8M
HSRD VA SDR 02-237NIDDK NIH HHS K24 DK091419NIDDK NIH HHS U01 DK102163
6 · The paper itself

Abstract

backgroundPrevious studies reported that compared with percutaneous coronary interventions (PCIs), coronary artery bypass grafting (CABG) is associated with a reduced risk of mortality and repeat revascularization in patients with mild to moderate chronic kidney disease (CKD) and end-stage renal disease (ESRD). Information about outcomes associated with CABG versus PCI in patients with advanced stages of CKD is limited. We evaluated the incidence and relative risk of acute kidney injury (AKI) associated with CABG versus PCI in patients with advanced CKD.

methodsWe examined 730 US veterans with incident ESRD who underwent a first CABG or PCI up to 5 years prior to dialysis initiation. The association of CABG versus PCI with AKI was examined in multivariable adjusted logistic regression analyses.

resultsA total of 466 patients underwent CABG and 264 patients underwent PCI. The mean age was 64 ± 8 years, 99% were male, 20% were African American and 84% were diabetic. The incidence of AKI in the CABG versus PCI group was 67% versus 31%, respectively (P < 0.001). The incidence of all stages of AKI were higher after CABG compared with PCI. CABG was associated with a 4.5-fold higher crude risk of AKI {odds ratio [OR] 4.53 [95% confidence interval (CI) 3.28-6.27]; P < 0.001}, which remained significant after multivariable adjustments [OR 3.50 (95% CI 2.03-6.02); P < 0.001].

conclusionCABG was associated with a 4.5-fold higher risk of AKI compared with PCI in patients with advanced CKD. Despite other benefits of CABG over PCI, the extremely high risk of AKI associated with CABG should be considered in this vulnerable population when deciding on the optimal revascularization strategy.

Indexed as

Acute Kidney InjuryCohort StudiesCoronary Artery BypassFemaleHumansIncidenceMaleMiddle AgedPercutaneous Coronary InterventionRenal Insufficiency, ChronicTreatment OutcomeUnited Statesacute kidney injurychronic kidney diseasecoronary artery bypass graftingpercutaneous coronary interventions

Identifiers

PMID29986054
PMCPMC7967886
OpenAlexW2818306284

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.