Evidence map›Paper›PMID 29986016›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2019

Dialysis Catheter-related Bloodstream Infections in Patients Receiving Hemodialysis on an Emergency-only Basis: A Retrospective Cohort Analysis.

Hal H Zhang, Nicolás W Cortés-Penfield, Sreedhar Mandayam, Jingbo Niu, Robert L Atmar, Eric Wu, Daniel Chen, Roya Zamani, Maulin K Shah

Abstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hal H ZhangDepartment of Medicine, Baylor College of Medicine, Houston.
Nicolás W Cortés-PenfieldDepartment of Medicine, Section of Infectious Diseases, Baylor College of Medicine, Houston.
Sreedhar MandayamDepartment of Medicine, Baylor College of Medicine, Houston.
Jingbo NiuDepartment of Medicine, Section of Nephrology, Baylor College of Medicine, Houston.
Robert L AtmarDepartment of Medicine, Section of Infectious Diseases, Baylor College of Medicine, Houston.
Eric WuDepartment of Medicine, Baylor College of Medicine, Houston.
Daniel ChenDepartment of Pediatrics, University of Texas Southwestern, Dallas.
Roya ZamaniDepartment of Medicine, Baylor College of Medicine, Houston.
Maulin K ShahDepartment of Medicine, Section of Nephrology, Baylor College of Medicine, Houston.

Funding

Research Training in Infections and ImmunityT32AI055413 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI GIORDANO, THOMAS P, MYSOREKAR, INDIRA U · 2003 to 2024
$3.2M
NIAID NIH HHS T32 AI055413
6 · The paper itself

Abstract

backgroundAn estimated 6500 undocumented immigrants with end-stage renal disease (ESRD) live in the United States. Those living in states that do not provide undocumented immigrants scheduled hemodialysis receive intermittent hemodialysis only when life-threatening conditions arise. Little is known about catheter-related bloodstream infections (CRBSIs) in this population.

methodsWe conducted a retrospective cohort study of emergency-only hemodialysis patients in the Harris Health System in Houston, Texas, between January 2012 and December 2015. We assessed CRBSI risk factors including demographics, comorbidities, and duration and frequency of hemodialysis. We investigated the microbiologic etiology of these infections, rates of recurrent CRBSI, and associated morbidity and mortality.

resultsThe cohort included 329 patients; 90% were Hispanic, 60% had diabetes, and the average age was 51 years. A total of 101 CRBSIs occurred, with a rate of 0.84 infections per 1000 catheter-days. Cirrhosis and duration of hemodialysis during the study period were associated with increased risk of CRBSI. Seventeen CRBSIs were recurrent; infection with gram-positive bacteria predicted recurrence. Adherence to catheter-related infection guidelines was improved by infectious diseases consultation and associated with fewer recurrent infections. CRBSI was associated with prolonged hospitalization (mean, 15 days), composite complication rate of 8%, and a 4% mortality rate.

conclusionsPatients receiving emergency-only hemodialysis via tunneled catheters have a high CRBSI rate compared with infection rates previously reported in patients receiving scheduled maintenance hemodialysis. Increased CRSBI risk likely contributes to the increased morbidity and mortality seen in ESRD patients receiving emergency-only hemodialysis.

Indexed as

Emergency Medical ServicesAdultAgedCatheter-Related InfectionsCohort StudiesDisease ManagementFemaleHumansKidney Failure, ChronicMaleMiddle AgedRenal DialysisRetrospective StudiesSepsisCRBSIemergency hemodialysisESRDhemodialysis catheterundocumented

Identifiers

PMID29986016
PMCPMC6399430

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.