Evidence map›Paper›PMID 29985980›Full record

ArticleChemical senses2018

Automated analysis of breathing waveforms using BreathMetrics: a respiratory signal processing toolbox.

Torben Noto, Guangyu Zhou, Stephan Schuele, Jessica Templer, Christina Zelano

Open access · bronzeAbstract read
In one paragraph

Article in Chemical senses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 88 citations in OpenAlex.

  1. Article
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  5. Science advances · 2026
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  8. Respiration Shapes the Neural Dynamics of Successful Remembering in Humans.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  9. Article
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  13. Evidence That Respiratory Phase May Modulate Task-Related Neural Representations of Visual Stimuli.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
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  14. Article
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  18. Breathing orchestrates synchronization of sleep oscillations in the human hippocampus.Proceedings of the National Academy of Sciences of the United States of America · 2024
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  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Torben NotoDepartment of Neurology, Northwestern University Feinberg School of Medicine, Ward, Chicago, IL, USA.
Guangyu ZhouDepartment of Neurology, Northwestern University Feinberg School of Medicine, Ward, Chicago, IL, USA.
Stephan SchueleDepartment of Neurology, Northwestern University Feinberg School of Medicine, Ward, Chicago, IL, USA.
Jessica TemplerDepartment of Neurology, Northwestern University Feinberg School of Medicine, Ward, Chicago, IL, USA.
Christina ZelanoDepartment of Neurology, Northwestern University Feinberg School of Medicine, Ward, Chicago, IL, USA.
Northwestern University · US

Funding

TRAINING PROGRAM IN THE NEUROSCIENCE OF HUMAN COGNITIONT32NS047987 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Rodrigo M Braga, Christina Maria Zelano · 2006 to 2026
$5.6M
The function of respiratory-linked local field potential oscillations in human olfactory and limbic brain regionsR01DC016364 · NIDCD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ZELANO, CHRISTINA MARIA · 2018 to 2022
$2.1M
Attention-dependent neural oscillations in the human olfactory systemR00DC012803 · NIDCD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ZELANO, CHRISTINA MARIA · 2015 to 2017
$732k
NIDCD NIH HHS R00 DC012803NIDCD NIH HHS R01 DC016364NINDS NIH HHS T32 NS047987
6 · The paper itself

Abstract

Nasal inhalation is the basis of olfactory perception and drives neural activity in olfactory and limbic brain regions. Therefore, our ability to investigate the neural underpinnings of olfaction and respiration can only be as good as our ability to characterize features of respiratory behavior. However, recordings of natural breathing are inherently nonstationary, nonsinusoidal, and idiosyncratic making feature extraction difficult to automate. The absence of a freely available computational tool for characterizing respiratory behavior is a hindrance to many facets of olfactory and respiratory neuroscience. To solve this problem, we developed BreathMetrics, an open-source tool that automatically extracts the full set of features embedded in human nasal airflow recordings. Here, we rigorously validate BreathMetrics' feature estimation accuracy on multiple nasal airflow datasets, intracranial electrophysiological recordings of human olfactory cortex, and computational simulations of breathing signals. We hope this tool will allow researchers to ask new questions about how respiration relates to body, brain, and behavior.

Indexed as

RespirationAlgorithmsAutomationHumansNasal CavityOlfactory CortexOlfactory PerceptionReproducibility of Results

Identifiers

PMID29985980
PMCPMC6150778
OpenAlexW2834248954

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.