Evidence map›Paper›PMID 29985756›Full record

ArticleHuman vaccines & immunotherapeutics2018

Passive immunization with influenza haemagglutinin specific monoclonal antibodies.

Rajeev Rudraraju, Kanta Subbarao

Open access · bronzeAbstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Rajeev Rudrarajua WHO Collaborating Centre for Reference and Research on Influenza and the Department of Microbiology and Immunology , The Peter Doherty Institute for Infection and Immunity , Melbourne , Australia.
Kanta Subbaraoa WHO Collaborating Centre for Reference and Research on Influenza and the Department of Microbiology and Immunology , The Peter Doherty Institute for Infection and Immunity , Melbourne , Australia.ORCID 0000-0003-1713-3056
Peter Doherty Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The isolation of broadly neutralising antibodies against the influenza haemagglutinin has spurred investigation into their clinical potential, and has led to advances in influenza virus biology and universal influenza vaccine development. Studies in animal models have been invaluable for demonstrating the prophylactic and therapeutic efficacy of broadly neutralising antibodies, for comparisons with antiviral drugs used as the standard of care, and for defining their mechanism of action and potential role in providing protection from airborne infection.

Indexed as

AnimalsAntibodies, MonoclonalAntibodies, NeutralizingAntibodies, ViralCross ProtectionDisease Models, AnimalDrug Evaluation, PreclinicalHemagglutinin Glycoproteins, Influenza VirusHumansImmunization, PassiveInfluenza A virusInfluenza, HumanMiceTreatment OutcomeAntibodies, MonoclonalAntibodies, NeutralizingAntibodies, ViralHemagglutinin Glycoproteins, Influenza Virusbroadly neutralising antibodiesHA stemInfluenzamonoclonal antibodiespassive immunization

Identifiers

PMID29985756
PMCPMC6314409
OpenAlexW2846437485

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.