Evidence map›Paper›PMID 29985484›Full record

ArticleScientific reports2018

High-density Genotyping reveals Genomic Characterization, Population Structure and Genetic Diversity of Indian Mithun (Bos frontalis).

Anupama Mukherjee, Sabyasachi Mukherjee, Rajan Dhakal, Moonmoon Mech, Imsusosang Longkumer, Nazrul Haque, Kezhavituo Vupru, Kobu Khate, I Yanger Jamir, Pursenla Pongen and 4 more

Abstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Anupama MukherjeeAnimal Genetics and Breeding Lab., ICAR-National Research Centre on Mithun, Medziphema, Nagaland, 797106, India.
Sabyasachi MukherjeeAnimal Genetics and Breeding Lab., ICAR-National Research Centre on Mithun, Medziphema, Nagaland, 797106, India. sabayasachimukherje@gmail.com.
Rajan DhakalCenter for Quantitative Genetics and Genomics, Department of Molecular Biology and Genetics, Aarhus University, 8830, Tjele, Denmark.ORCID 0000-0003-0036-2100
Moonmoon MechAnimal Genetics and Breeding Lab., ICAR-National Research Centre on Mithun, Medziphema, Nagaland, 797106, India.
Imsusosang LongkumerAnimal Genetics and Breeding Lab., ICAR-National Research Centre on Mithun, Medziphema, Nagaland, 797106, India.
Nazrul HaqueAnimal Genetics and Breeding Lab., ICAR-National Research Centre on Mithun, Medziphema, Nagaland, 797106, India.
Kezhavituo VupruAnimal Genetics and Breeding Lab., ICAR-National Research Centre on Mithun, Medziphema, Nagaland, 797106, India.
Kobu KhateAnimal Genetics and Breeding Lab., ICAR-National Research Centre on Mithun, Medziphema, Nagaland, 797106, India.
I Yanger JamirAnimal Genetics and Breeding Lab., ICAR-National Research Centre on Mithun, Medziphema, Nagaland, 797106, India.
Pursenla PongenAnimal Genetics and Breeding Lab., ICAR-National Research Centre on Mithun, Medziphema, Nagaland, 797106, India.
Chandan RajkhowaAnimal Genetics and Breeding Lab., ICAR-National Research Centre on Mithun, Medziphema, Nagaland, 797106, India.
Abhijit MitraAnimal Genetics and Breeding Lab., ICAR-National Research Centre on Mithun, Medziphema, Nagaland, 797106, India.
Bernt GuldbrandtsenCenter for Quantitative Genetics and Genomics, Department of Molecular Biology and Genetics, Aarhus University, 8830, Tjele, Denmark.ORCID 0000-0003-1764-135X
Goutam SahanaCenter for Quantitative Genetics and Genomics, Department of Molecular Biology and Genetics, Aarhus University, 8830, Tjele, Denmark.ORCID 0000-0001-7608-7577

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current study aimed at genomic characterization and improved understanding of genetic diversity of two Indian mithun populations (both farm, 48 animals and field, 24 animals) using genome wide genotype data generated with Illumina BovineHD BeadChip. Eight additional populations of taurine cattle (Holstein and NDama), indicine cattle (Gir) and other evolutionarily closely related species (Bali cattle, Yak, Bison, Gaur and wild buffalo) were also included in this analysis (N = 137) for comparative purposes. Our results show that the genetic background of mithun populations was uniform with few possible signs of indicine admixture. In general, observed and expected heterozygosities were quite similar in these two populations. We also observed increased frequencies of small-sized runs of homozygosity (ROH) in the farm population compared to field mithuns. On the other hand, longer ROH were more frequent in field mithuns, which suggests recent founder effects and subsequent genetic drift due to close breeding in farmer herds. This represents the first study providing genetic evidence about the population structure and genomic diversity of Indian mithun. The information generated will be utilized for devising suitable breeding and conservation programme for mithun, an endangered bovine species in India.

Indexed as

Genetic VariationGenomePopulation DynamicsAnimalsCattleEndangered SpeciesGenotypeHomozygoteIndiaPhylogenyPrincipal Component Analysis

Identifiers

PMID29985484
PMCPMC6037757

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.