Evidence map›Paper›PMID 29985311›Full record

ArticleJournal of visualized experiments : JoVE2018

PET Imaging of Neuroinflammation Using [11C]DPA-713 in a Mouse Model of Ischemic Stroke.

Aisling M Chaney, Emily M Johnson, Haley C Cropper, Michelle L James

Abstract readVideo-Audio Media
In one paragraph

Article in Journal of visualized experiments : JoVE, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Illuminating proinflammatory myeloid cells with PET tracers targeting GPR84.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Contrast-enhanced TScientific reports · 2026
    Article
  3. Article
  4. Diagnostic Value ofFrontiers in oncology · 2022
    Article
  5. Whole-body PET Imaging of T-cell Response to Glioblastoma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2021
    Article
  6. Imaging of Cancer γ-Secretase Activity Using an Inhibitor-Based PET Probe.Clinical cancer research : an official journal of the American Association for Cancer Research · 2021
    Article
  7. Imaging Tumor-Infiltrating Lymphocytes in Brain Tumors with [Clinical cancer research : an official journal of the American Association for Cancer Research · 2021
    Article
  8. Review
  9. Demarcation of Sepsis-Induced Peripheral and Central Acidosis with pH (Low) Insertion Cycle Peptide.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2020
    Article
  10. Review
  11. Article
  12. Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Aisling M ChaneyDepartment of Radiology, Stanford University.
Emily M JohnsonDepartment of Radiology, Stanford University.
Haley C CropperDepartment of Radiology, Stanford University.
Michelle L JamesDepartment of Radiology, Stanford University; Department of Neurology and Neurological Sciences, Stanford University; mljames@stanford.edu.
Stanford University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroinflammation is central to the pathological cascade following ischemic stroke. Non-invasive molecular imaging methods have the potential to provide critical insights into the temporal dynamics and role of certain neuroimmune interactions in stroke. Specifically, Positron Emission Tomography (PET) imaging of translocator protein 18 kDa (TSPO), a marker of activated microglia and peripheral myeloid-lineage cells, provides a means to detect and track neuroinflammation in vivo. Here, we present a method to accurately quantify neuroinflammation using [

Indexed as

AnimalsBrainBrain IschemiaCarbon RadioisotopesDisease Models, AnimalInflammationMagnetic Resonance ImagingMicePositron-Emission TomographyStrokeCarbon-11Carbon Radioisotopes

Identifiers

PMID29985311
PMCPMC6101726
OpenAlexW2807775880

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.