Evidence map›Paper›PMID 29985095›Full record

Trial reportMultiple sclerosis (Houndmills, Basingstoke, England)2019

Impact of mindfulness-based stress reduction for people with multiple sclerosis at 8 weeks and 12 months: A randomized clinical trial.

Angela Senders, Douglas Hanes, Dennis Bourdette, Kimberly Carson, Lynn M Marshall, Lynne Shinto

2 registry-linked trialsOpen access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Multiple sclerosis (Houndmills, Basingstoke, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 14 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 4 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06433544 nacompletednot on this mapstarted 2022, after this paper: background citation

Evaluating the Effects of Online Mindfulness Therapy on Pandemic Fatigue and Resilience Among Nurses in COVID-19 Quarantine Wards

TypeinterventionalSponsorChimei Medical CenterRan2022 to 2023Enrolled60ConditionsMindfulness, Nurses in COVID-19, Pandemic Fatigue, ResilienceArms6-week online mindfulness course
NCT07741864 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Effectiveness of a Mindfulness-Based Intervention for Pain Management in Patients With Multiple Sclerosis

TypeinterventionalSponsorHospital Universitario Virgen MacarenaRan2026 to 2027Enrolled84ConditionsMultiple Sclerosis, Pain, Pain ManagementArmsMindfulness-based intervention, Educational intervention
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 4 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Individual Resilience Interventions: A Systematic Review in Adult Population Samples over the Last Decade.International journal of environmental research and public health · 2021
    Pooled it
  5. Trial
  6. Article
  7. Article
  8. Article
  9. Article
  10. Effectiveness of Mindfulness-based Stress Reduction Program in Improving Mental Well-being of Patients with COVID-19: A Randomized Controlled Trial.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2022
    Article
  11. Article
  12. Article
  13. The impact of resilience on healthy aging with multiple sclerosis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Angela SendersHelfgott Research Institute, National University of Natural Medicine, Portland, OR, USA/Department of Neurology, Oregon Health & Science University, Portland, OR, USA/OHSU-PSU School of Public Health, Portland, OR, USA.ORCID 0000-0003-2507-4818
Douglas HanesHelfgott Research Institute, National University of Natural Medicine, Portland, OR, USA.
Dennis BourdetteDepartment of Neurology, Oregon Health & Science University, Portland, OR, USA.
Kimberly CarsonDepartment of Anesthesiology & Perioperative Medicine, Oregon Health & Science University, Portland, OR, USA.
Lynn M MarshallDepartment of Orthopedics and Rehabilitation, Oregon Health & Science University, Portland, OR, USA/OHSU-PSU School of Public Health, Portland, OR, USA.
Lynne ShintoDepartment of Neurology, Oregon Health & Science University, Portland, OR, USA.
Oregon Health & Science University · USNational University of Natural Medicine · US

Funding

OREGON CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTEUL1RR024140 · NCRR · OREGON HEALTH & SCIENCE UNIVERSITY · PI ORWOLL, ERIC S. · 2006 to 2011
$61.1M
Mindfulness-based Stress Reduction for Multiple Sclerosis: Feasibility, Durability, and Clinical OutcomesK23AT008211 · NCCIH · NATIONAL UNIVERSITY OF NATURAL MEDICINE · PI SENDERS, ANGELA · 2015 to 2019
$673k
NCCIH NIH HHS K23 AT008211NCRR NIH HHS UL1 RR024140
6 · The paper itself

Abstract

backgroundMindfulness training is often used as a therapeutic intervention to manage stress and enhance emotional well-being, yet trials for multiple sclerosis (MS) are limited and few have used an active control.

objectiveAssess the feasibility of mindfulness-based stress reduction (MBSR) for people with MS and evaluate the efficacy of MBSR compared to an education control.

methodsWe conducted a single-blind, randomized trial of MBSR versus education control among 62 adults with MS. Primary outcomes were measures of feasibility. Secondary outcomes included perceived stress, anxiety, depression, fatigue, pain, resilience, and the Paced Auditory Serial Addition Test, assessed at baseline, 8 weeks, and 12 months. Mean scores for secondary outcome measures were compared between groups at each time point and within groups across time by analyses of covariance or paired

resultsSuccessful recruitment and retention demonstrated feasibility. Improvements in several secondary outcomes were observed among both MBSR and control groups. However, differences between the groups were not statistically significant at either 8 weeks or 12 months.

conclusionEmotional well-being improved with both MBSR and education. Spontaneous improvement cannot be ruled out as an explanation for findings and additional studies that evaluate the impact of mindfulness training to improve emotional health are warranted.

Indexed as

Outcome Assessment, Health CareAdultFeasibility StudiesFemaleFollow-Up StudiesHumansMaleMiddle AgedMindfulnessMultiple SclerosisPsychotherapy, GroupSingle-Blind MethodStress, PsychologicalanxietymindfulnessMultiple sclerosispsychological stressquality of liferesilience

Identifiers

PMID29985095
PMCPMC6386630
OpenAlexW2872349819

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.