ReviewThe Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry2019
Purkinje Cell Representations of Behavior: Diary of a Busy Neuron.
Review in The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed.
- Cerebellar Transcranial Alternating Current Stimulation in the Theta Band Prevents Recall of the Initial Fear Association After Extinction Training.Human brain mapping · 2026Trial
- Consensus Paper: Models of Cerebellar Functions.Cerebellum (London, England) · 2026Review
- Cerebellar Purkinje cell firing reduction contributes to aging-related declining motor coordination in mice.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Plasma membrane calcium ATPases and cerebellar pathology: what's the role in the ataxia?Biology direct · 2025Review
- Amyloid precursor protein modulates cerebellar Purkinje cell activity and motor function through regulation of Nav1.6 currents.PLoS biology · 2025Article
- The Association Between Clinically Diagnosed Neonatal Jaundice and Autism: A Swedish Register-Based Cohort Study.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Cerebellar circuit computations for predictive motor control.Nature reviews. Neuroscience · 2025Review
- TMEM106B deficiency leads to alterations in lipid metabolism and obesity in the TDP-43Communications biology · 2025Article
- Immediate Neuroplastic Changes in the Cortex After iTBS on the Cerebellum of Stroke Patients: A Preliminary fNIRS Study.Neural plasticity · 2025Article
- Article
- Genetic Deletion of Thorase Causes Purkinje Cell Loss and Impaired Motor Coordination Behavior.Cells · 2023Article
- The little brain and the seahorse: Cerebellar-hippocampal interactions.Frontiers in systems neuroscience · 2023Review
- The cerebellum and anxiety.Frontiers in cellular neuroscience · 2023Article
- Cerebellar contributions across behavioural timescales: a review from the perspective of cerebro-cerebellar interactions.Frontiers in systems neuroscience · 2023Review
- Cerebellar GABA Change during Visuomotor Adaptation Relates to Adaptation Performance and Cerebellar Network Connectivity: A Magnetic Resonance Spectroscopic Imaging Study.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Cerebellar Representations of Errors and Internal Models.Cerebellum (London, England) · 2022Review
- Article
- ATR regulates neuronal activity by modulating presynaptic firing.Nature communications · 2021Article
- Utilizing an Animal Model to Identify Brain Neurodegeneration-Related Biomarkers in Aging.International journal of molecular sciences · 2021Article
- Functional Imaging of the Cerebellum during Action Execution and Observation.Cerebral cortex communications · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Fundamental for understanding cerebellar function is determining the representations in Purkinje cell activity, the sole output of the cerebellar cortex. Up to the present, the most accurate descriptions of the information encoded by Purkinje cells were obtained in the context of motor behavior and reveal a high degree of heterogeneity of kinematic and performance error signals encoded. The most productive framework for organizing Purkinje cell firing representations is provided by the forward internal model hypothesis. Direct tests of this hypothesis show that individual Purkinje cells encode two different forward models simultaneously, one for effector kinematics and one for task performance. Newer results demonstrate that the timing of simple spike encoding of motor parameters spans an extend interval of up to ±2 seconds. Furthermore, complex spike discharge is not limited to signaling errors, can be predictive, and dynamically controls the information in the simple spike firing to meet the demands of upcoming behavior. These rich, diverse, and changing representations highlight the integrative aspects of cerebellar function and offer the opportunity to generalize the cerebellar computational framework over both motor and non-motor domains.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.