Evidence map›Paper›PMID 29984913›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2018

Does gender affect the association between right ventricular strain and arterial hypertension?

Marijana Tadic, Cesare Cuspidi, Branislava Ivanovic, Biljana Pencic, Guido Grassi, Vera Celic

Abstract read
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Marijana TadicDepartment of Cardiology, University Clinical Hospital Center "Dr. Dragisa Misovic - Dedinje,", Belgrade, Serbia.ORCID 0000-0002-6235-5152
Cesare CuspidiClinical Research Unit, University of Milan-Bicocca and Istituto Auxologico Italiano, Meda, Italy.ORCID 0000-0002-7689-478X
Branislava IvanovicClinical Centre of Serbia, Cardiology Clinic, Belgrade, Serbia.
Biljana PencicDepartment of Cardiology, University Clinical Hospital Center "Dr. Dragisa Misovic - Dedinje,", Belgrade, Serbia.
Guido GrassiClinica Medica, University of Milano Bicocca and IRCCS Multimedica Sesto San Giovanni, Milano, Italy.ORCID 0000-0003-1922-6547
Vera CelicDepartment of Cardiology, University Clinical Hospital Center "Dr. Dragisa Misovic - Dedinje,", Belgrade, Serbia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The importance of right ventricular (RV) structure and function in cardiovascular and total morbidity and mortality has been confirmed previously. The purpose of this study was to evaluate the influence of gender on RV structure and function in untreated hypertensive patients. This cross-sectional study included 243 subjects who underwent 24-hour ambulatory blood pressure (BP) monitoring and comprehensive echocardiographic examination including strain evaluation. There was no difference in RV diameter between hypertensive and normotensive women and men. RV wall thickness, right atrial volume index (RAVI), and tricuspid E/e' ratio were significantly higher in hypertensive women and men than in their normotensive counterparts. RV global longitudinal and RV free wall longitudinal strains were significantly lower in hypertensive women and men than in their normotensive counterparts. Arterial hypertension affected RV wall thickness, RAVI, tricuspid E/e', and RV longitudinal strain. Gender affected RV diameter, RAVI, tricuspid E/e', and RV longitudinal strain, whereas hypertension-gender interaction affected RAVI, E/e', and RV longitudinal strain. The 24-hour systolic BP and LV mass index were independently associated with RV free wall longitudinal strain. RV wall thickness was independently associated with RV free wall longitudinal strain only in women, and tricuspid E/e' was independently associated only in men. In conclusion, RV longitudinal strain was significantly decreased in hypertensive patients in both sexes. Hypertensive men suffered more evident RV mechanical changes than hypertensive women. Gender, arterial hypertension, and their interaction had the important role in RV structural and mechanical remodeling.

Indexed as

HypertensionVentricular Dysfunction, RightAdultBlood Pressure Monitoring, AmbulatoryEchocardiographyFemaleHeart VentriclesHumansMaleMiddle AgedOrgan SizeSerbiaSex FactorsVentricular Function, Rightarterial hypertensiongenderlongitudinal strainright ventricle

Identifiers

PMID29984913
PMCPMC8031281

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.