Evidence map›Paper›PMID 29984902›Full record

ArticleVeterinary medicine and science2018

Rifaximin anti-inflammatory activity on bovine endometrium primary cell cultures: a preliminary study.

Lisa Flammini, Leonardo Mantelli, Alessandra Volpe, Giuseppe Domenichini, Rosanna Di Lecce, Maurizio Dondi, Anna Maria Cantoni, Elisabetta Barocelli, Fausto Quintavalla

Open access · goldAbstract read
In one paragraph

Article in Veterinary medicine and science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Lisa FlamminiFood and Drug Department, University of Parma, Parma, Italy.ORCID 0000-0002-8871-6526
Leonardo MantelliDepartment of Medical Veterinary Sciences, University of Parma, Parma, Italy.
Alessandra VolpeFood and Drug Department, University of Parma, Parma, Italy.
Giuseppe DomenichiniFood and Drug Department, University of Parma, Parma, Italy.
Rosanna Di LecceDepartment of Medical Veterinary Sciences, University of Parma, Parma, Italy.
Maurizio DondiDepartment of Medical Veterinary Sciences, University of Parma, Parma, Italy.
Anna Maria CantoniDepartment of Medical Veterinary Sciences, University of Parma, Parma, Italy.
Elisabetta BarocelliFood and Drug Department, University of Parma, Parma, Italy.
Fausto QuintavallaDepartment of Medical Veterinary Sciences, University of Parma, Parma, Italy.
University of Parma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rifaximin is an unabsorbed oral antibiotic showing anti-inflammatory properties in human pathologies like irritable bowel syndrome and inflammatory bowel disease. In veterinary medicine, rifaximin is primarily used in the treatment of dermatological diseases in all animal species, in therapy and prophylaxis of mastitis in cows and in the treatment of endometritis in cattle and horses. The aim of this preliminary study was to evaluate the anti-inflammatory properties of rifaximin on primary cell cultures from bovine endometrium in which inflammatory response was induced by Lipopolysaccaride (LPS) treatment. Epithelial and stromal cells were isolated from bovine endometrium and separately incubated for 24 h with 1 μg mL

Indexed as

CattleAnimalsAnti-Bacterial AgentsCells, CulturedCell SurvivalEndometriumEpithelial CellsFemaleInflammationLipopolysaccharidesRifaximinAnti-Bacterial AgentsLipopolysaccharidesRifaximinBovinecell culturesendometriuminflammationrifaximin

Identifiers

PMID29984902
PMCPMC6236135
OpenAlexW2825982510

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.