Evidence map›Paper›PMID 29984802›Full record

ReviewActa otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale2018

Genes important for otoneurological diagnostic purposes - current status and future prospects.

K Pawlak-Osiñska, K Linkowska, T Grzybowski

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

K Pawlak-OsiñskaDepartment of Otolaryngology and Oncology Collegium Medicum in Bydgoszcz Nicolaus Copernicus University, Skłodowskiej-Curie 9, Bydgoszcz, Poland.
K LinkowskaDepartment of Forensic Medicine Division of Molecular and Forensic Genetics Collegium Medicum in Bydgoszcz Nicolaus Copernicus University, Skłodowskiej-Curie 9, Bydgoszcz, Poland.
T GrzybowskiDepartment of Forensic Medicine Division of Molecular and Forensic Genetics Collegium Medicum in Bydgoszcz Nicolaus Copernicus University, Skłodowskiej-Curie 9, Bydgoszcz, Poland.
Nicolaus Copernicus University · PLCollegium Medicum in Bydgoszcz · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

summaryThis review focuses on the current knowledge of the genes responsible for non-syndromic hearing loss that can be useful for otoneurological diagnostic purposes. From among a large number of genes that have been associated with non-syndromic hearing impairment, we selected several best-known genes, including the COCH gene, GJB2, GJB6 and SLC26A4, and we describe their role and effects of mutations and prevalence of mutations in various populations. Next, we focus on genes associated with tinnitus. Important areas for further research include assessment of genes potentially involved in pathophysiology of tinnitus and vertigo, which have traditionally been considered as being of otological aetiology, while advances in neuroimaging techniques have increasingly shifted studies toward neurological correlations.

Indexed as

Diagnostic Techniques, NeurologicalDiagnostic Techniques, OtologicalForecastingHearing LossHumansEpilepsyGeneticsHearing impairmentTinnitusVertigo

Identifiers

PMID29984802
PMCPMC6036948
OpenAlexW2808086679

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.