ArticleAIDS research and human retroviruses2018
Low Levels of Physical Activity Among Older Persons Living with HIV/AIDS Are Associated with Poor Physical Function.
Article in AIDS research and human retroviruses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Facilitators and barriers to physical activity in middle-aged and older adult(s) HIV infected persons: a systematic review of qualitative studies.Frontiers in public health · 2026Pooled it
- Effect of HIV on respiratory symptoms, health status, and exertional capacity.AIDS (London, England) · 2025Pooled it
- Barriers and Facilitators of Physical Activity in People Living With HIV: A Systematic Review of Qualitative Studies.Journal of the International Association of Providers of AIDS CarePooled it
- A randomized controlled trial to unveil the influence of an exercise intervention on brain integrity and gut microbiome structure in individuals with HIV.AIDS (London, England) · 2026Trial
- Physical activity and exercise for older people living with HIV - the perceptions of health care professionals.SAHARA J : journal of Social Aspects of HIV/AIDS Research Alliance · 2025Article
- Challenges to Physical Activity Participation Among Older People Living with HIV: Scoping Review.International journal of environmental research and public health · 2025Article
- Perceived quality of life and associated lifestyle practices among older people living with HIV in Uganda. A cross-sectional study.Virusdisease · 2025Article
- Impact of Body Mass Index and VO2 Max on Symptoms, Physical Activity, and Physical Function in a Multinational Sample of People with HIV.AIDS and behavior · 2025Article
- Design and rationale for a randomized clinical trial testing the efficacy of a lifestyle physical activity intervention for people with HIV and engaged in unhealthy drinking.Contemporary clinical trials · 2024Article
- Article
- The perceptions of older people living with hiv/aids towards physical activity and exercise.AIDS research and therapy · 2022Article
- Frailty in older people living with HIV: current status and clinical management.BMC geriatrics · 2022Review
- The Role of Depressive Symptoms and Physical Activity Levels in Mediating the Association Between HIV Status and Neurocognitive Functions Among Individuals Aged at Least 50 Years in China: Cross-sectional Study.JMIR public health and surveillance · 2022Article
- Comparison of diet, muscle strength, steps per day and symptoms in people with HIV and HIV-negative peers.Research in nursing & health · 2022Article
- Physical Activity and Exercise for Older People Living with HIV: A Scoping Review.HIV/AIDS (Auckland, N.Z.) · 2021Article
- Application of Selected Muscle Strength and Body Mass Cut Points for the Diagnosis of Sarcopenia in Men and Women With or at Risk for HIV Infection.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020Article
- The Impact of a Structured, Supervised Exercise Program on Daily Step Count in Sedentary Older Adults With and Without HIV.Journal of acquired immune deficiency syndromes (1999) · 2020Article
- Self-rated eyesight and handgrip strength in older adults.Wiener klinische Wochenschrift · 2020Article
- Physical activity among women of low socioeconomic status living with HIV in two major cities of Brazil and Mozambique: A cross-sectional comparative study.Clinics (Sao Paulo, Brazil) · 2020Article
- Effects of Exercise on the Immune Function, Quality of Life, and Mental Health in HIV/AIDS Individuals.Advances in experimental medicine and biology · 2020Review
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
Antiretroviral therapy (ART) has prolonged lives of persons living with HIV/AIDS (PLWHA), resulting in greater incidence of aging-related diseases and disability. Physical activity (PA) is recommended for healthy aging, but little is known about PA in older PLWHA. The purpose of this study was to objectively assess PA levels in older PLWHA and the associations with physical function. Twenty-one PLWHA, ≥50 years old, on ART with undetectable HIV-1 viral loads, wore an accelerometer to assess PA, including number of steps, activity intensity, and energy expenditure over 7 days. A physical function performance battery assessing aerobic capacity, strength, and gait speed was also completed. Average age was 66, and 67% were male. An average of 3,442 (interquartile range: 4,613) steps were walked daily, with 254.9 kcals expended. Participants spent most waking hours (75%) sedentary, with minimal hours (24%) in light-intensity activity. Only 5 min per day (35 min per week), on average, were spent in moderate-to-vigorous physical activity (MVPA). Maximal gait speed and 6-min walk test significantly correlated (p < .05) with all PA outcomes. Usual gait speed significantly correlated with all PA outcomes, except for daily kcals and light-intensity activity. Greater PA was associated with better physical performance, while high sedentary time was associated with poorer performance. To our knowledge, this is the first study to objectively measure PA in older PLWHA. Our findings indicate that older PLWHA accumulate substantial sedentary time. Most (86%) do not achieve recommended MVPA levels. This activity profile was associated with poor physical function. Providers should promote PA among PLWHA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.