Evidence map›Paper›PMID 29984260›Full record

ArticleMovement disorders clinical practice

Quick Flicks: Association of Paroxysmal Kinesigenic Dyskinesia and Tics.

Bettina Balint, Sarah Wiethoff, Davide Martino, Claudia Del Gamba, Anna Latorre, Christos Ganos, Henry Houlden, Kailash P Bhatia

Open access · hybridAbstract read
In one paragraph

Article in Movement disorders clinical practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. A Musician's Journey with PRRT2 Related Paroxysmal Dyskinesia.Movement disorders clinical practice · 2022
    Article
  3. Tics in Paroxysmal Kinesigenic Dyskinesia.Movement disorders clinical practice · 2019
    Article
  4. Reply to: Tics in Paroxysmal Kinesigenic Dyskinesia.Movement disorders clinical practice · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 4 countries.

Bettina BalintSobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology Queen Square London UK.
Sarah WiethoffCenter for Neurology and Hertie Institute for Clinical Brain Research Eberhard Karls-University Tübingen Germany.
Davide MartinoDepartment of Clinical Neurosciences University of Calgary Canada.
Claudia Del GambaNeurology Unit, Department of Clinical and Experimental Medicine University of Pisa.
Anna LatorreSobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology Queen Square London UK.
Christos GanosDepartment of Neurology University Medical Center, Hamburg-Eppendorf (UKE) Hamburg Germany.ORCID 0000-0001-8077-8530
Henry HouldenDepartment of Molecular Neuroscience, UCL Institute of Neurology Queen Square London UK.
Kailash P BhatiaSobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology Queen Square London UK.ORCID 0000-0001-8185-286X
Sobell House · GBHeidelberg University · DEHertie Institute for Clinical Brain Research · DENational Hospital for Neurology and Neurosurgery · GBUniversität Hamburg · DEUniversity of Calgary · CAUniversity of Pisa · IT

Funding

Wellcome Trust
6 · The paper itself

Abstract

backgroundParoxysmal kinesigenic dyskinesia (PKD) is a rare disorder characterised by brief attacks of chorea, dystonia, or mixed forms precipitated by sudden movement.

methodsObservational study with a cohort of 14 PKD patients and genetic testing for

resultsIn a series of 14 PKD patients seen in our clinic at the National Hospital of Neurology, Queen Square, from 2012-2017, we noted tics in 11 patients (79%), which stand in stark contrast to the estimated lifetime prevalence of tics estimated to reach 1%.

conclusionsThe two reasons to point out this possible association are the clinical implications and the potential opportunity of a better understanding of shared pathophysiological mechanisms of neuronal hyperexcitability.

Indexed as

paroxysmal kinesigenic dyskinesia (PKD)PRRT2tics

Identifiers

PMID29984260
PMCPMC6016019
OpenAlexW2900012975

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.