Evidence map›Paper›PMID 29984259›Full record

ReviewJournal of immunology research2018

Adverse Immunologically Mediated Oral Mucosal Reactions to Systemic Medication: Lichenoid Tissue Reaction/Interface Dermatitis-Stomatitis, Autoimmune Vesiculobullous Disease, and IgE-Dependent and Immune Complex Reactions.

R A G Khammissa, R Chandran, A Masilana, J Lemmer, L Feller

Open access · goldAbstract readReview
In one paragraph

Review in Journal of immunology research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Amlodipine-induced buccal lichenoid lesions: A case report.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

R A G KhammissaDepartment of Periodontology and Oral Medicine, Sefako Makgatho Health Sciences University, Pretoria, South Africa.ORCID 0000-0002-8599-8249
R ChandranDepartment of Periodontology and Oral Medicine, Sefako Makgatho Health Sciences University, Pretoria, South Africa.
A MasilanaDepartment of Periodontology and Oral Medicine, Sefako Makgatho Health Sciences University, Pretoria, South Africa.
J LemmerDepartment of Periodontology and Oral Medicine, Sefako Makgatho Health Sciences University, Pretoria, South Africa.
L FellerDepartment of Periodontology and Oral Medicine, Sefako Makgatho Health Sciences University, Pretoria, South Africa.ORCID 0000-0001-8209-153X
Sefako Makgatho Health Sciences University · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drug-induced hypersensitivity immune reactions are exaggerated immunoinflammatory responses to allergenic components of the medications that occur in genetically susceptible subjects. The type of hypersensitivity immune response generated, whether antibody mediated or T cell mediated, or an immune complex reaction is determined by multiple factors, including the molecular characteristics of the allergen, the route of administration of the medication, the manner of presentation of the allergen by antigen-presenting cells to naïve T cells, the repertoire of the T cell receptors, and the cytokine profile within the microenvironment. This review deals with the clinical and histopathological aspects of adverse immunologically mediated oral mucosal reactions to systemic medication. We elaborate on diseases showing features of lichenoid tissue reaction/interface dermatitis-stomatitis, autoimmune vesiculobullous oral lesions, and immunoglobulin E- (IgE-) and immune complex-mediated oral reactions to drugs.

Indexed as

AllergensAnaphylaxisAntigen-Antibody ComplexAntigen-Antibody ReactionsAutoimmune DiseasesDrug EruptionsDrug HypersensitivityErythema MultiformeHumansImmunoglobulin ELichenoid EruptionsLichen PlanusMouth DiseasesMouth MucosaSkin Diseases, VesiculobullousStomatitisAllergensAntigen-Antibody ComplexImmunoglobulin E

Identifiers

PMID29984259
PMCPMC6015680
OpenAlexW2805743228

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.