Evidence map›Paper›PMID 29984251›Full record

ArticleBioMed research international2018

Real-World Results of Aflibercept versus Ranibizumab for the Treatment of Exudative AMD Using a Fixed Regimen.

Joana Providência, Tiago M Rodrigues, Mariana Oliveira, João Bernardes, João Pedro Marques, Joaquim Murta, Rufino Silva

Abstract read
In one paragraph

Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Real-world safety and efficacy of Anti-VEGF treatment in Brazil.Arquivos brasileiros de oftalmologia · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Joana ProvidênciaDepartment of Ophthalmology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.ORCID 0000-0003-1312-7978
Tiago M RodriguesDepartment of Ophthalmology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.
Mariana OliveiraDepartment of Ophthalmology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.
João BernardesDepartment of Ophthalmology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.
João Pedro MarquesDepartment of Ophthalmology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.ORCID 0000-0002-1014-0483
Joaquim MurtaDepartment of Ophthalmology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.
Rufino SilvaDepartment of Ophthalmology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intravitreal injections of antivascular endothelial growth factors have been considered a milestone in the treatment of neovascular age-related macular degeneration (nAMD). However, the increasing incidence of AMD and the burden of visits and injections overcharge both the patient and the healthcare systems. Real-world solutions depend on treatment protocols aimed at optimizing the number of clinical visits while guaranteeing good functional outcomes. We performed a retrospective analysis of 72 eyes from 63

Indexed as

AgedAged, 80 and overAngiogenesis InhibitorsFemaleFollow-Up StudiesHumansIntravitreal InjectionsMacular DegenerationMaleRanibizumabReceptors, Vascular Endothelial Growth FactorRecombinant Fusion ProteinsRetrospective StudiesTomography, Optical CoherenceTreatment OutcomeVisual AcuityafliberceptAngiogenesis InhibitorsRanibizumabReceptors, Vascular Endothelial Growth FactorRecombinant Fusion Proteins

Identifiers

PMID29984251
PMCPMC6011153

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.