Evidence map›Paper›PMID 29984237›Full record

ArticleBioMed research international2018

Long-Lasting Alterations in Gene Expression of Postsynaptic Density 95 and Inotropic Glutamatergic Receptor Subunit in the Mesocorticolimbic System of Rat Offspring Born to Morphine-Addicted Mothers.

Pei-Ling Wu, Yung-Ning Yang, Jau-Ling Suen, Yu-Chen S H Yang, Chun-Hwa Yang, San-Nan Yang

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
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  5. Enhanced H3K4 Trimethylation in TNF-Mediators of inflammation · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Pei-Ling WuDepartment of Pediatrics, E-DA Hospital, Kaohsiung, Taiwan.
Yung-Ning YangDepartment of Pediatrics, E-DA Hospital, Kaohsiung, Taiwan.
Jau-Ling SuenGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Yu-Chen S H YangJoint Biobank, Office of Human Research, Taipei Medical University, Taipei, Taiwan.ORCID 0000-0002-7589-8527
Chun-Hwa YangDepartment of Pediatrics, E-DA Hospital, Kaohsiung, Taiwan.
San-Nan YangDepartment of Pediatrics, E-DA Hospital, Kaohsiung, Taiwan.ORCID 0000-0003-1276-8546
Kaohsiung Medical University · TWE-Da Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prenatal exposure to morphine causes altered glutamatergic neurotransmission, which plays an important pathophysiological role for neurobiological basis of opiate-mediated behaviors in such offspring. However, it is still not clear whether such alteration involves gene expression of ionotropic glutamate receptor subunits. In this study, we further studied whether prenatal morphine exposure resulted in long-term changes in the gene expression of

Indexed as

Post-Synaptic DensityAnalgesics, OpioidAnimalsFemaleMorphineMorphine DependenceMothersPregnancyPrenatal Exposure Delayed EffectsRatsRats, Sprague-DawleyReceptors, AMPAReceptors, N-Methyl-D-AspartateAnalgesics, OpioidMorphineReceptors, AMPAReceptors, N-Methyl-D-Aspartate

Identifiers

PMID29984237
PMCPMC6015726
OpenAlexW2806207328

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.