Evidence map›Paper›PMID 29984179›Full record

ArticleIntegrative medicine research2018

Muhammad Maqsood, Rahmatullah Qureshi, Masroor Ikram, M Sheeraz Ahmad, Bushra Jabeen, Muhammad Rafique Asi, Junaid Ahmed Khan, Safdar Ali, Lothar Lilge

Open access · goldAbstract read
In one paragraph

Article in Integrative medicine research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Comprehensive analysis of3 Biotech · 2025
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  5. Review
  6. Review
  7. Investigation of bioactive compounds inBiotechnology reports (Amsterdam, Netherlands) · 2020
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  8. In vitro anticancer activity ofEXCLI journal · 2020
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  9. Article
  10. Potent antitumor property of Allium bakhtiaricum extracts.BMC complementary and alternative medicine · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Muhammad MaqsoodDepartment of Botany, Pir Mehr Ali Shah Arid Agriculture University, Rawalpindi, Pakistan.
Rahmatullah QureshiDepartment of Botany, Pir Mehr Ali Shah Arid Agriculture University, Rawalpindi, Pakistan.
Masroor IkramPhotomedicine Research Lab., Pakistan Institute of Engineering & Applied Sciences, Islamabad, Pakistan.
M Sheeraz AhmadDepartment of Biochemistry, Pir Mehr Ali Shah Arid Agriculture University, Rawalpindi, Pakistan.
Bushra JabeenDepartment of Biochemistry, Pir Mehr Ali Shah Arid Agriculture University, Rawalpindi, Pakistan.
Muhammad Rafique AsiNuclear Institute of Agriculture & Biology, Faisalabad, Pakistan.
Junaid Ahmed KhanPhotomedicine Research Lab., Pakistan Institute of Engineering & Applied Sciences, Islamabad, Pakistan.
Safdar AliUniversity Health Network, Princess Margaret Cancer Centre, Toronto, Canada.
Lothar LilgeUniversity Health Network, Princess Margaret Cancer Centre, Toronto, Canada.
Pir Mehr Ali Shah Arid Agriculture University · PKPakistan Institute of Engineering and Applied Sciences · PKUniversity Health Network · CANuclear Institute for Agriculture and Biology · PKUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Pakistani Salt Range has a rich floral diversity including

methodsThe crude methanolic extracts of the root, leaf, leaf stalk, and fruit of this plant were screened for their cytotoxic activity against human (HeLa, MCF-7, RD) and rat (RG2 and INS-1) cancer cell lines at 20 μg/mL and compared to methotrexate. The IC

resultsThe leaf stalk extract showed the highest cytotoxic efficacy against all tested cell lines, with IC

conclusionThe present study gives a scientific insight and comparative analysis of various plant parts in this medicinally important plant species from the Salt Range of Pakistan against both human and rat cancer cells.

Indexed as

AnticancerPresto Blue cell metabolic assayTotal flavonoid contentsTotal phenolic contents

Identifiers

PMID29984179
PMCPMC6026361
OpenAlexW2794920399

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.