ArticleBiomedical optics express2018
Selective retina therapy enhanced with optical coherence tomography for dosimetry control and monitoring: a proof of concept study.
Article in Biomedical optics express, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 14 citations in OpenAlex.
- Selective Retina Therapy With Fundus Image-Based Titration in Central Serous Chorioretinopathy: Prospective Outcomes and Predictive Factors.Translational vision science & technology · 2026Article
- Interferometric thermometry of ocular tissues for retinal laser therapy.Biomedical optics express · 2023Article
- Algorithms for optoacoustically controlled selective retina therapy (SRT).Photoacoustics · 2022Article
- Optical dosimeter for selective retinal therapy based on multi-port fiber-optic interferometry.Biomedical optics express · 2021Article
- Selective retina therapy monitoring by speckle variance optical coherence tomography for dosimetry control.Journal of biomedical optics · 2020Article
- Selective retina therapy enhanced with optical coherence tomography for dosimetry control and monitoring: a proof of concept study.Biomedical optics express · 2018Article
- Motion-invariant SRT treatment detection from direct M-scan OCT imaging.International journal of computer assisted radiology and surgery · 2018Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Selective treatment of the retinal pigment epithelium (RPE) by using short-pulse lasers leads to a less destructive treatment for certain retinal diseases in contrast to conventional photocoagulation. The introduction of selective retina therapy (SRT) to clinical routine is still precluded by the challenges to reliably monitor treatment success and to automatically adjust dose within the locally varying therapeutic window. Combining micrometer-scale depth resolving capabilities of optical coherence tomography (OCT) with SRT can yield real-time information on the laser-induced changes within the RPE after a laser pulse or even during treatment with a laser pulse train. In the present study, SRT and OCT were combined to treat ex-vivo porcine eyes demonstrating closed-loop dose-control. We found a reliable correlation of specific signal changes in time resolved OCT images and physiological lesions in the RPE. First experiments, including 23 porcine eyes, prove the feasibility of the novel treatment concept.
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Registered trials
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