Evidence map›Paper›PMID 29984088›Full record

ArticleBiomedical optics express2018

Volumetric optical coherence microscopy with a high space-bandwidth-

Siyang Liu, Jeffrey A Mulligan, Steven G Adie

Abstract read
In one paragraph

Article in Biomedical optics express, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Siyang LiuSchool of Electrical and Computer Engineering, Cornell University, Ithaca, NY 14853, USA.
Jeffrey A MulliganSchool of Electrical and Computer Engineering, Cornell University, Ithaca, NY 14853, USA.
Steven G AdieNancy E. and Peter C. Meinig School of Biomedical Engineering, Cornell University, Ithaca, NY 14853, USA.

Funding

Development of Hybrid Adaptive Optics for Multimodal Microscopy Deep in the Mouse BrainR21EY028389 · NEI · CORNELL UNIVERSITY · PI ADIE, STEVEN GRAHAM · 2017 to 2018
$491k
NEI NIH HHS R21 EY028389
6 · The paper itself

Abstract

Optical coherence microscopy (OCM) is a promising modality for high resolution imaging, but has limited ability to capture large-scale volumetric information about dynamic biological processes with cellular resolution. To enhance the throughput of OCM, we implemented a hybrid adaptive optics (hyAO) approach that combines computational adaptive optics with an intentionally aberrated imaging beam generated via hardware adaptive optics. Using hyAO, we demonstrate the depth-equalized illumination and collection ability of an astigmatic beam compared to a Gaussian beam for cellular-resolution imaging. With this advantage, we achieved volumetric OCM with a higher space-bandwidth-

Indexed as

(110.1080) Active or adaptive optics(110.3010) Image reconstruction techniques(170.4500) Optical coherence tomography(170.6900) Three-dimensional microscopy

Identifiers

PMID29984088
PMCPMC6033577

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.