ArticleBiomedical optics express2018
Pixel-wise segmentation of severely pathologic retinal pigment epithelium and choroidal stroma using multi-contrast Jones matrix optical coherence tomography.
Article in Biomedical optics express, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 23 citations in OpenAlex.
- Evaluation of focal damage in the retinal pigment epithelium layer in serous retinal pigment epithelium detachment.Scientific reports · 2019Trial
- Evaluation of retinal pigment epithelium changes in serous pigment epithelial detachment using synthesized multi-contrast polarization-sensitive optical coherence tomography.Scientific reports · 2025Article
- Comparative study of OCTA algorithms with a high-sensitivity multi-contrast Jones matrix OCT system for human skin imaging.Biomedical optics express · 2022Article
- Computational refocusing of Jones matrix polarization-sensitive optical coherence tomography and investigation of defocus-induced polarization artifacts.Biomedical optics express · 2022Article
- Three-dimensional dynamics optical coherence tomography for tumor spheroid evaluation.Biomedical optics express · 2021Article
- Framework for quantitative three-dimensional choroidal vasculature analysis using optical coherence tomography.Biomedical optics express · 2021Article
- Evaluation of retinal pigment epithelium changes in serous pigment epithelial detachment in age-related macular degeneration.Scientific reports · 2021Observational
- Optical coherence tomography-based tissue dynamics imaging for longitudinal and drug response evaluation of tumor spheroids.Biomedical optics express · 2020Article
- Clinical multi-functional OCT for retinal imaging.Biomedical optics express · 2019Article
- Polarization-sensitive optical coherence elastography.Biomedical optics express · 2019Article
- Directional optical coherence tomography reveals melanin concentration-dependent scattering properties of retinal pigment epithelium.Journal of biomedical optics · 2019Article
- Multi-scale and -contrast sensorless adaptive optics optical coherence tomography.Quantitative imaging in medicine and surgery · 2019Article
- Clinical prototype of pigment and flow imaging optical coherence tomography for posterior eye investigation.Biomedical optics express · 2018Article
- Machine-learning based segmentation of the optic nerve head using multi-contrast Jones matrix optical coherence tomography with semi-automatic training dataset generation.Biomedical optics express · 2018Article
- Imaging retinal melanin: a review of current technologies.Journal of biological engineering · 2018Review
- Advances in multimodal imaging in ophthalmology.Therapeutic advances in ophthalmologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tissue segmentation of retinal optical coherence tomography (OCT) is widely used in ophthalmic diagnosis. However, its performance in severe pathologic cases is still insufficient. We propose a pixel-wise segmentation method that uses the multi-contrast measurement capability of Jones matrix OCT (JM-OCT). This method is applicable to both normal and pathologic retinal pigment epithelium (RPE) and choroidal stroma. In this method, "features," which are sensitive to specific tissues of interest, are synthesized by combining the multi-contrast images of JM-OCT, including attenuation coefficient, degree-of-polarization-uniformity, and OCT angiography. The tissue segmentation is done by simple thresholding of the feature. Compared with conventional segmentation methods for pathologic maculae, the proposed method is less computationally intensive. The segmentation method was validated by applying it to images from normal and severely pathologic cases. The segmentation results enabled the development of several types of
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.